(Q42819037)

7 November 2017

title

Differential effects of novel tumour-derived p53 mutations on the transformation of NIH-3T3 cells (English)

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7 November 2017

Howard Donninger

1

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7 November 2017

Anke Binder

series ordinal

2

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7 November 2017

Lothar Bohm

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3

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7 November 2017

M Iqbal Parker

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4

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7 November 2017

language of work or name

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1 January 2008

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7 November 2017

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7 November 2017

volume

389

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7 November 2017

issue

1

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7 November 2017

page(s)

57-67

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p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

7 November 2017

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Radiosensitization and DNA repair inhibition by pentoxifylline in NIH3T3 p53 transfectants

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Mutant p53 protects cells from 12-O-tetradecanoylphorbol-13-acetate-induced death by attenuating activating transcription factor 3 induction

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Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

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WAF1, a potential mediator of p53 tumor suppression

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Transformation of normal human fibroblasts into immortalized cells with the mutant p53 gene and X-rays

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A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

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Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1

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An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

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Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies

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Mutations of the p53 gene as a prognostic factor in aggressive B-cell lymphoma.

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Oligomerization is not essential for growth suppression by p53 in p53-deficient osteosarcoma Saos-2 cells

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Oncogenic forms of p53 inhibit p53-regulated gene expression

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Wild-type p53 is a cell cycle checkpoint determinant following irradiation

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Cancer. p53, guardian of the genome

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Mutant p53 protein expression interferes with p53-independent apoptotic pathways

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

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Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells

21 January 2018

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Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

21 January 2018

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Comparison of the effect of mutant and wild-type p53 on global gene expression

21 January 2018

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Over-expression of p53 mutants in LNCaP cells alters tumor growth and angiogenesis in vivo.

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Tumor-derived p53 mutants induce oncogenesis by transactivating growth-promoting genes.

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Modulation of gene expression by tumor-derived p53 mutants

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Isolation of Temperature-sensitive p53 Mutations from a Comprehensive Missense Mutation Library

21 January 2018

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Overexpression of p53 protein is an independent prognostic indicator in human endometrial carcinoma

21 January 2018

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Cellular accumulation of p53 protein: an independent prognostic factor in stage II breast cancer

21 January 2018

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p53-R175H mutant gains new function in regulation of doxorubicin-induced apoptosis

21 January 2018

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Molecular and cellular responses to DNA damage in a murine pituitary adenoma cell line

21 January 2018

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p21 is a universal inhibitor of cyclin kinases

21 January 2018

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Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73

21 January 2018

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Prognostic significance of cytoplasmic p53 overexpression in colorectal cancer. An immunohistochemical analysis

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1515/BC.2008.010

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7 November 2017

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