(Q42823550)

English

ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis

scientific article published on 15 October 2007

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scholarly article

1 reference

Europe PubMed Central

8 November 2017

ATF4-dependent oxidative induction of the DNA repair enzyme Ape1 counteracts arsenite cytotoxicity and suppresses arsenite-mediated mutagenesis (English)

1 reference

Europe PubMed Central

8 November 2017

0 references

author name string

Hua Fung

1

1 reference

Europe PubMed Central

8 November 2017

Pingfang Liu

2

1 reference

Europe PubMed Central

8 November 2017

Bruce Demple

3

1 reference

Europe PubMed Central

8 November 2017

language of work or name

0 references

publication date

15 October 2007

1 reference

Europe PubMed Central

8 November 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

8 November 2017

27

1 reference

Europe PubMed Central

8 November 2017

24

1 reference

Europe PubMed Central

8 November 2017

8834-8847

1 reference

Europe PubMed Central

8 November 2017

DNA repair protein involved in heart and blood development

1 reference

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27 May 2018

As(III) transcriptionally activates the gadd45a gene via the formation of H2O2

1 reference

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27 May 2018

Roles of base excision repair subpathways in correcting oxidized abasic sites in DNA.

1 reference

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27 May 2018

Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA

1 reference

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27 May 2018

Molecular and biological roles of Ape1 protein in mammalian base excision repair

1 reference

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27 May 2018

Apoptosis: mechanisms and relevance in cancer

1 reference

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27 May 2018

Two essential but distinct functions of the mammalian abasic endonuclease

1 reference

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27 May 2018

The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism

1 reference

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27 May 2018

A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells.

1 reference

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27 May 2018

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

1 reference

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27 May 2018

AP endonuclease-independent DNA base excision repair in human cells

1 reference

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27 May 2018

APE1 is the major 3'-phosphoglycolate activity in human cell extracts

1 reference

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27 May 2018

Activating transcription factor 4 increases the cisplatin resistance of human cancer cell lines.

1 reference

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27 May 2018

The adaptive imbalance in base excision-repair enzymes generates microsatellite instability in chronic inflammation.

1 reference

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27 May 2018

AP-1: a double-edged sword in tumorigenesis

1 reference

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27 May 2018

Mechanism of arsenic carcinogenesis: an integrated approach

1 reference

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27 May 2018

Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

All roads lead to ATF4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Effect of arsenic on transcription factor AP-1 and NF-kappaB DNA binding activity and related gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Key role of a downstream specificity protein 1 site in cell cycle-regulated transcription of the AP endonuclease gene APE1/APEX in NIH3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Arsenite induces oxidative DNA adducts and DNA-protein cross-links in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Roles of yeast DNA polymerases delta and zeta and of Rev1 in the bypass of abasic sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Recent advances in the protocols of transgenic mouse mutation assays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Going APE over ref-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

A method for detecting abasic sites in living cells: age-dependent changes in base excision repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Presence of activating transcription factor 4 (ATF4) in the porcine anterior pituitary

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

A multihit, multistage model of chemical carcinogenesis

1 reference

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27 May 2018

Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Loss of normal G1 checkpoint control is an early step in carcinogenesis, independent of p53 status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

p53 is involved in but not required for ionizing radiation-induced caspase-3 activation and apoptosis in human lymphoblast cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Comparison of the promoters of the mouse (APEX) and human (APE) apurinic endonuclease genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Asbestos increases mammalian AP-endonuclease gene expression, protein levels, and enzyme activity in mesothelial cells

1 reference

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27 May 2018

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Cytotoxic and mutagenic responses to X-rays and chemical mutagens in normal and p53-mutated human lymphoblastoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Repair of oxidative damage to DNA: enzymology and biology

1 reference

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27 May 2018

Programmed cell death and mutation induction in AHH-1 human lymphoblastoid cells exposed to m-amsa

1 reference

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27 May 2018

Intracellular localization of the Apn1 DNA repair enzyme of Saccharomyces cerevisiae. Nuclear transport signals and biological role.

1 reference

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27 May 2018

Incision activity of human apurinic endonuclease (Ape) at abasic site analogs in DNA

1 reference

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27 May 2018

Characterization of the promoter region of the human apurinic endonuclease gene (APE).

1 reference

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27 May 2018

Escherichia coli xth mutants are hypersensitive to hydrogen peroxide

1 reference

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27 May 2018

Comparison of arsenic-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture.

1 reference

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27 May 2018

Mutagenesis by apurinic/apyrimidinic sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Mechanism of comutagenesis of sodium arsenite with n-methyl-n-nitrosourea

1 reference

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27 May 2018

Comutagenesis of sodium arsenite with ultraviolet radiation in Chinese hamster V79 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Promoter-selective activation domains in Oct-1 and Oct-2 direct differential activation of an snRNA and mRNA promoter

1 reference

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27 May 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

27 May 2018

Low dose exposure to sodium arsenite synergistically interacts with UV radiation to induce mutations and alter DNA repair in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

16 August 2018

Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

16 August 2018

Activating transcription factor 4 is required for the differentiation of the lamina propria layer of the vas deferens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

16 August 2018

Arsenite induces delayed mutagenesis and transformation in human osteosarcoma cells at extremely low concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

16 August 2018

Induction of oxidative DNA damage by arsenite and its trivalent and pentavalent methylated metabolites in cultured human cells and isolated DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

16 August 2018

Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

16 August 2018

Apurinic/apyrimidinic endonuclease activity is elevated in human adult gliomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

16 August 2018

Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in inner Mongolia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2169401

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Effect of metals on mutagenesis and DNA repair

1 reference

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16 August 2018

MDM2 gene amplification and transcript levels in human sarcomas: relationship to TP53 gene status

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

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inferred from PubMed ID database lookup

Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of apurinic/apyrimidinic endonuclease (Ape, Ref-1) by oxidative stress requires CREB

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer research. Inflammation and cancer: the link grows stronger

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated and altered expression of the multifunctional DNA base excision repair and redox enzyme Ape1/ref-1 in prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of an apurinic/apyrimidinic endonuclease from HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous DNA damage stimulates topoisomerase II-mediated DNA cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative genotoxic potency of arsenic and its methylated metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The apurinic/apyrimidinic endonuclease (APE/ref-1) DNA repair enzyme is elevated in premalignant and malignant cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17938202

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00974-07

1 reference

https://api.fatcat.wiki/v0/release/3mjfj75wsfh23odjqcramf76xe

30 July 2022

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mapped directly with Wikidata item

release_3mjfj75wsfh23odjqcramf76xe

1 reference

https://api.fatcat.wiki/v0/release/3mjfj75wsfh23odjqcramf76xe

30 July 2022

based on heuristic

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/3mjfj75wsfh23odjqcramf76xe

30 July 2022

based on heuristic

mapped directly with Wikidata item

1 reference

https://api.fatcat.wiki/v0/release/3mjfj75wsfh23odjqcramf76xe

30 July 2022

based on heuristic

mapped directly with Wikidata item

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