(Q24338600)

Granzyme B

1 reference

Granzyme A

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SET nuclear proto-oncogene

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DNA-(apurinic or apyrimidinic site) lyase

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1 reference

7

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author name string

Zusen Fan

1

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Paul J Beresford

2

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Dong Zhang

3

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Zhan Xu

4

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Carl D Novina

5

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Akira Yoshida

6

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Judy Lieberman

Lymphocyte-mediated cytotoxicity.

8

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language of work or name

English

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publication date

February 2003

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published in

Nature Immunology

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volume

4

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page(s)

145-53

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issue

2

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cites work

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Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

21 January 2018

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HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

21 January 2018

1 reference

Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them

21 January 2018

1 reference

Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks

21 January 2018

1 reference

21 January 2018

Going APE over ref-1.

1 reference

An 'environment to nucleus' signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

21 January 2018

1 reference

Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway

21 January 2018

1 reference

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

21 January 2018

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Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo.

21 January 2018

1 reference

Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.

21 January 2018

1 reference

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

21 January 2018

1 reference

Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

21 January 2018

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

21 January 2018

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Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.

21 January 2018

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The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

21 January 2018

1 reference

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding

21 January 2018

1 reference

The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA.

21 January 2018

1 reference

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

21 January 2018

1 reference

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

21 January 2018

1 reference

Importance of poly(ADP-ribose) polymerase and its cleavage in apoptosis. Lesson from an uncleavable mutant

21 January 2018

1 reference

Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs

21 January 2018

1 reference

Tumor suppression and potentiation by manipulation of pp32 expression

21 January 2018

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Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators

21 January 2018

1 reference

Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein

21 January 2018

1 reference

Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex.

21 January 2018

1 reference

The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing

21 January 2018

1 reference

Identification of in vivo phosphorylation sites of SET, a nuclear phosphoprotein encoded by the translocation breakpoint in acute undifferentiated leukemia

21 January 2018

1 reference

Cellular localization and expression of template-activating factor I in different cell types.

21 January 2018

1 reference

Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system

21 January 2018

1 reference

A natural killer cell granule protein that induces DNA fragmentation and apoptosis

21 January 2018

1 reference

Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

21 January 2018

1 reference

7 January 2021

Creation of a fully functional human chimeric DNA repair protein. Combining O6-methylguanine DNA methyltransferase (MGMT) and AP endonuclease (APE/redox effector factor 1 (Ref 1)) DNA repair proteins

1 reference

7 January 2021

Overexpression of Ref-1 inhibits hypoxia and tumor necrosis factor-induced endothelial cell apoptosis through nuclear factor-kappab-independent and -dependent pathways

1 reference

7 January 2021

Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1

1 reference

7 January 2021