(Q42824450)

8 November 2017

Requirement for PAK4 in the anchorage-independent growth of human cancer cell lines (English)

1 reference

8 November 2017

Marinella G Callow

1

1 reference

8 November 2017

Felix Clairvoyant

2

1 reference

8 November 2017

Shirley Zhu

3

1 reference

8 November 2017

Brian Schryver

4

1 reference

8 November 2017

David B Whyte

5

1 reference

8 November 2017

James R Bischoff

6

1 reference

8 November 2017

Bahija Jallal

7

1 reference

8 November 2017

Tod Smeal

8

1 reference

8 November 2017

language of work or name

English

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publication date

19 October 2001

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Journal of Biological Chemistry

8 November 2017

1 reference

8 November 2017

277

1 reference

8 November 2017

550-558

1 reference

8 November 2017

1

1 reference

The Ste20 group kinases as regulators of MAP kinase cascades

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Structure of Cdc42 bound to the GTPase binding domain of PAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A novel regulator of p21-activated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Temporal and spatial distribution of activated Pak1 in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Neutrophils stimulated with a variety of chemoattractants exhibit rapid activation of p21-activated kinases (Paks): separate signals are required for activation and inactivation of paks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A role for p21-activated kinase in endothelial cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Actin cytoskeleton organization regulated by the PAK family of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Regulation of the protein kinase Raf-1 by oncogenic Ras through phosphatidylinositol 3-kinase, Cdc42/Rac and Pak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A role for Rho in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A role for Pak protein kinases in Schwann cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The Akt proto-oncogene links Ras to Pak and cell survival signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A domain containing the Cdc42/Rac interactive binding (CRIB) region of p65PAK inhibits transcriptional activation and cell transformation mediated by the Ras-Rac pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Regulation of microfilament reorganization and invasiveness of breast cancer cells by kinase dead p21-activated kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Endogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Activated PAK4 regulates cell adhesion and anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Biological assays for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Cell adhesion regulates the interaction between Nck and p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Thymic lymphoma induction by the AKT8 murine retrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

The Dbl family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Oligomerization of DH domain is essential for Dbl-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Regulatable Expression of p21-activated Kinase-1 Promotes Anchorage-independent Growth and Abnormal Organization of Mitotic Spindles in Human Epithelial Breast Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

Amplification of 19q13.1–q13.2 sequences in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105732200

21 January 2018

Identifiers

DOI

10.1074/JBC.M105732200

1 reference

8 November 2017

1 reference