(Q42824871)

8 November 2017

title

UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9. (English)

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8 November 2017

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7

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8 November 2017

Xiaoli Liu

1

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8 November 2017

Qinqin Gao

2

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8 November 2017

Pishun Li

3

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8 November 2017

Qian Zhao

4

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8 November 2017

Jiqin Zhang

5

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8 November 2017

Jiwen Li

6

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8 November 2017

Jiemin Wong

8

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8 November 2017

language of work or name

English

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publication date

1 January 2013

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8 November 2017

published in

Nature Communications

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8 November 2017

volume

4

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8 November 2017

page(s)

1563

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DNA methylation and gene silencing in cancer

8 November 2017

cites work

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12 December 2020

Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation

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12 December 2020

UHRF1, a modular multi-domain protein, regulates replication-coupled crosstalk between DNA methylation and histone modifications

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12 December 2020

Cloning and mapping of Np95 gene which encodes a novel nuclear protein associated with cell proliferation

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12 December 2020

Aberrant DNA methylation as a cancer-inducing mechanism

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12 December 2020

Coordinated chromatin control: structural and functional linkage of DNA and histone methylation

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12 December 2020

Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein

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12 December 2020

Relationship between histone H3 lysine 9 methylation, transcription repression, and heterochromatin protein 1 recruitment.

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12 December 2020

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

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12 December 2020

Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism

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12 December 2020

UHRF1 double tudor domain and the adjacent PHD finger act together to recognize K9me3-containing histone H3 tail

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12 December 2020

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

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12 December 2020

The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites

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12 December 2020

Linking DNA methylation and histone modification: patterns and paradigms

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12 December 2020

DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells

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12 December 2020

S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance

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12 December 2020

EUKARYOTIC CYTOSINE METHYLTRANSFERASES

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12 December 2020

Rb targets histone H3 methylation and HP1 to promoters

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12 December 2020

Multiple domains are involved in the targeting of the mouse DNA methyltransferase to the DNA replication foci

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12 December 2020

The multi-domain protein Np95 connects DNA methylation and histone modification.

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12 December 2020

DNA methylation patterns and epigenetic memory

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12 December 2020

VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization

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12 December 2020

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation

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12 December 2020

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

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12 December 2020

Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells

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12 December 2020

Np95 is a histone-binding protein endowed with ubiquitin ligase activity

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12 December 2020

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

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12 December 2020

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

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12 December 2020

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

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12 December 2020

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

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12 December 2020

The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix

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12 December 2020

The mammalian epigenome

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12 December 2020

Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1

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12 December 2020

Temporal and spatial localization of novel nuclear protein NP95 in mitotic and meiotic cells

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12 December 2020

Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1

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12 December 2020

The PHD domain of Np95 (mUHRF1) is involved in large-scale reorganization of pericentromeric heterochromatin

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12 December 2020

Dynamic changes in subnuclear NP95 location during the cell cycle and its spatial relationship with DNA replication foci

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12 December 2020

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

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12 December 2020

Mammalian DNA methyltransferases: a structural perspective

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12 December 2020

ICBP90 belongs to a new family of proteins with an expression that is deregulated in cancer cells

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12 December 2020

ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain

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12 December 2020

UHRF1 plays a role in maintaining DNA methylation in mammalian cells

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS2562

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8 November 2017

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