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DNA methylation and gene silencing in cancer
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
DNA methylation and gene silencing in cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
main subject
gene silencing
0 references
DNA methylation
0 references
author name string
Stephen B Baylin
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
publication date
1 December 2005
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
published in
Nature Clinical Practice Oncology
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
volume
2 Suppl 1
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
page(s)
S4-11
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
exact match
https://scigraph.springernature.com/pub.10.1038/ncponc0354
0 references
cites work
Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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21 January 2018
DNA methylation patterns and epigenetic memory
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The fundamental role of epigenetic events in cancer
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
based on heuristic
inferred from DOI database lookup
Gene silencing in cancer in association with promoter hypermethylation
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients with myelodysplasia and acute myeloid leukemia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
based on heuristic
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The DNA methyltransferases of mammals
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reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
based on heuristic
inferred from DOI database lookup
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
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https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
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inferred from DOI database lookup
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
based on heuristic
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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpG methylation is maintained in human cancer cells lacking DNMT1.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methyltransferase Dnmt1 associates with histone deacetylase activity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
based on heuristic
inferred from DOI database lookup
Translating the Histone Code
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
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7 January 2021
based on heuristic
inferred from DOI database lookup
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transitions in distinct histone H3 methylation patterns at the heterochromatin domain boundaries
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation-induced repression--belts, braces, and chromatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical development of histone deacetylase inhibitors as anticancer agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two genetic hits (more or less) to cancer
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypermethylation of tumor suppressor genes in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation as a target for drug design
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation: past, present and future directions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting hypomethylation of DNA to achieve cellular differentiation in myelodysplastic syndromes (MDS).
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methyltransferase inhibitors-state of the art.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNCPONC0354
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NCPONC0354
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
Dimensions Publication ID
1034769071
0 references
PubMed ID
16341240
1 reference
stated in
Europe PubMed Central
PubMed ID
16341240
retrieved
13 August 2017
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