(Q54755048)

English

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia.

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scholarly article

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia. (English)

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

1 reference

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author name string

Christiansen DH

1

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

Andersen MK

2

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

Pedersen-Bjergaard J

3

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

publication date

1 September 2003

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Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

17

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

1813-1819

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

9

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

https://scigraph.springernature.com/pub.10.1038/sj.leu.2403054

0 references

Cancer cell cycles

1 reference

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21 January 2018

The RB and p53 pathways in cancer

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

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Expression and regulation of G1 cell-cycle inhibitors (p16INK4A, p15INK4B, p18INK4C, p19INK4D) in human acute myeloid leukemia and normal myeloid cells

1 reference

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Expression of cyclin-dependent kinase inhibitor p15(INK4B) during normal and leukemic myeloid differentiation

1 reference

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Expression of p15(ink4b) gene during megakaryocytic differentiation of normal and myelodysplastic hematopoietic progenitors.

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Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells

1 reference

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21 January 2018

Causality of myelodysplasia and acute myeloid leukemia and their genetic abnormalities

1 reference

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

1 reference

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21 January 2018

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

1 reference

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High sensitivity mapping of methylated cytosines

1 reference

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Expression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.

1 reference

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21 January 2018

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment

1 reference

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21 January 2018

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Lineage-specific regulation of cell cycle control gene expression during haematopoietic cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

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Methylation of the p15(INK4B) gene in myelodysplastic syndrome: it can be detected early at diagnosis or during disease progression and is highly associated with leukaemic transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

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Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor progno

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

inferred from DOI database lookup

P15INK4B gene methylation and expression in normal, myelodysplastic, and acute myelogenous leukemia cells and in the marrow cells of cured lymphoma patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

inferred from DOI database lookup

A bisulfite method of 5-methylcytosine mapping that minimizes template degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

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Internal tandem duplications of the FLT3 and MLL genes are mainly observed in atypical cases of therapy-related acute myeloid leukemia with a normal karyotype and are unrelated to type of previous therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

inferred from DOI database lookup

Duplication or amplification of chromosome band 11q23, including the unrearranged MLL gene, is a recurrent abnormality in therapy-related MDS and AML, and is closely related to mutation of the TP53 gene and to previous therapy with alkylating agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylation of p15 and p16 genes in adult acute leukemia: lack of prognostic significance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylation of p15 and p16 genes in acute promyelocytic leukemia: potential diagnostic and prognostic significance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

inferred from DOI database lookup

Methylation status of the p15INK4B gene in hematopoietic progenitors and peripheral blood cells in myelodysplastic syndromes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403054

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.LEU.2403054

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

1 reference

Europe PubMed Central

3 June 2018

http://europepmc.org/abstract/MED/12970781

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