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Signaling to p53: breaking the MDM2-p53 circuit
scientific article published on 01 October 1998
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Signaling to p53: breaking the MDM2-p53 circuit
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
author name string
C Prives
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
language of work or name
English
0 references
publication date
1 October 1998
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
published in
Cell
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
volume
95
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
page(s)
5-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
cites work
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p14ARF links the tumour suppressors RB and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E1A signaling to p53 involves the p19ARFtumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional activation of p53 via phosphorylation following DNA damage by UV but not γ radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53: puzzle and paradigm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ultraviolet radiation, but not γ radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p19ARF links the tumour suppressor p53 to Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage induces phosphorylation of the amino terminus of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase acts upstream of p53 in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF Promotes MDM2 Degradation and Stabilizes p53: ARF-INK4a Locus Deletion Impairs Both the Rb and p53 Tumor Suppression Pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981774-2
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0092-8674(00)81774-2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
PubMed publication ID
9778240
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9778240
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778240%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
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