(Q42826185)

English

A novel snake venom vascular endothelial growth factor (VEGF) predominantly induces vascular permeability through preferential signaling via VEGF receptor-1.

scientific article published on 24 August 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 November 2017

A novel snake venom vascular endothelial growth factor (VEGF) predominantly induces vascular permeability through preferential signaling via VEGF receptor-1. (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

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author name string

Hiroyuki Takahashi

1

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Shosaku Hattori

2

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Akihiro Iwamatsu

3

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Hajime Takizawa

4

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

Masabumi Shibuya

5

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Europe PubMed Central

PubMed publication ID

8 November 2017

language of work or name

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publication date

24 August 2004

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Europe PubMed Central

PubMed publication ID

8 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

8 November 2017

279

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Europe PubMed Central

PubMed publication ID

8 November 2017

44

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

46304-46314

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

The biology of VEGF and its receptors

1 reference

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Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis

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Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

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Vascular endothelial growth factor is a secreted angiogenic mitogen

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Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid

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Vascular endothelial growth factor receptor-2: its unique signaling and specific ligand, VEGF-E.

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Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

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Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells

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Molecular mechanisms of lymphangiogenesis in health and disease

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A novel type of vascular endothelial growth factor, VEGF-E (NZ-7 VEGF), preferentially utilizes KDR/Flk-1 receptor and carries a potent mitotic activity without heparin-binding domain

1 reference

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A novel vascular endothelial growth factor encoded by Orf virus, VEGF-E, mediates angiogenesis via signalling through VEGFR-2 (KDR) but not VEGFR-1 (Flt-1) receptor tyrosine kinases

1 reference

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Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1

1 reference

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1 reference

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Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

1 reference

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Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

1 reference

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21 January 2018

Molecular cloning and expression of a functional snake venom vascular endothelium growth factor (VEGF) from the Bothrops insularis pit viper. A new member of the VEGF family of proteins.

1 reference

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21 January 2018

Complete structure of an increasing capillary permeability protein (ICPP) purified from Vipera lebetina venom. ICPP is angiogenic via vascular endothelial growth factor receptor signalling

1 reference

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21 January 2018

The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts

1 reference

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21 January 2018

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

1 reference

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21 January 2018

A set of loop-1 and -3 structures in the novel vascular endothelial growth factor (VEGF) family member, VEGF-ENZ-7, is essential for the activation of VEGFR-2 signaling

1 reference

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21 January 2018

Activation of ErbB3-PI3-kinase pathway is correlated with malignant phenotypes of adenocarcinomas

1 reference

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21 January 2018

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

1 reference

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21 January 2018

Snake Venom Vascular Endothelial Growth Factors (VEGFs) Exhibit Potent Activity through Their Specific Recognition of KDR (VEGF Receptor 2)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403687200

21 January 2018

Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor

1 reference

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21 January 2018

Receptor-selective variants of human vascular endothelial growth factor. Generation and characterization

1 reference

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21 January 2018

Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site

1 reference

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21 January 2018

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403687200

21 January 2018

VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

1 reference

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21 January 2018

Interactions of FLT-1 and KDR with phospholipase C gamma: identification of the phosphotyrosine binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403687200

21 January 2018

Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403687200

21 January 2018

The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403687200

21 January 2018

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

1 reference

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21 January 2018

A mutant form of vascular endothelial growth factor (VEGF) that lacks VEGF receptor-2 activation retains the ability to induce vascular permeability

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M403687200

21 January 2018

VEGF/VPF overexpression in skin of transgenic mice induces angiogenesis, vascular hyperpermeability and accelerated tumor development

1 reference

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21 January 2018

Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M403687200

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

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