(Q42829086)

8 November 2017

Differential requirement for Rho family GTPases in an oncogenic insulin-like growth factor-I receptor-induced cell transformation (English)

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8 November 2017

1 reference

Sachdev P

1

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8 November 2017

Jiang YX

2

1 reference

8 November 2017

Li W

3

1 reference

8 November 2017

Miki T

4

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8 November 2017

Maruta H

5

1 reference

8 November 2017

Nur-E-Kamal MS

6

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8 November 2017

Wang LH

7

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8 November 2017

language of work or name

English

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publication date

9 May 2001

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Journal of Biological Chemistry

8 November 2017

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8 November 2017

276

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8 November 2017

26461-26471

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8 November 2017

28

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Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor

8 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Treatment and prevention of rat glioblastoma by immunogenic C6 cells expressing antisense insulin-like growth factor I RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Growth factors and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Oncogenes, Protein Tyrosine Kinases, and Signal Transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

The role of the insulin-like growth factor I receptor in transformation and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Protein kinase C-delta is an important signaling molecule in insulin-like growth factor I receptor-mediated cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

The CDC42-specific inhibitor derived from ACK-1 blocks v-Ha-Ras-induced transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

A role for Rho in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Role of p85 subunit of phosphatidylinositol-3-kinase as an adaptor molecule linking the insulin receptor to insulin receptor substrate 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Inositol phosphates and cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Stat3 activation is required for cellular transformation by v-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK, Cas, and paxillin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Overexpression of human insulin receptor substrate 1 induces cellular transformation with activation of mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Ras-independent transformation by v-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

A mutant form of the rho protein can restore stress fibers and adhesion plaques in v-src transformed fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

v-src-induced cell shape changes in rat fibroblasts require new gene transcription and precede loss of focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

The Dbl family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Transformation mediated by RhoA requires activity of ROCK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Expression of insulin-like growth factor receptors in primary human thyroid neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Phospholipase C-gamma is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Differential regulation of focal adhesion kinase and mitogen-activated protein kinase tyrosine phosphorylation during insulin-like growth factor-I-mediated cytoskeletal reorganization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Transformation of mammalian cells by constitutively active MAP kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Insulin-like growth factor I (IGF-I) induces unique effects in the cytoskeleton of cultured rat glomerular mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Tyrosine phosphorylation of paxillin and focal adhesion kinase during insulin-like growth factor-I-stimulated lamellipodial advance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

Signaling to the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010995200

21 January 2018

Identifiers

DOI

10.1074/JBC.M010995200

1 reference

8 November 2017

1 reference