(Q42832284)

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Ameliorative effect of flunarizine in cisplatin-induced acute renal failure via mitochondrial permeability transition pore inactivation in rats.

scientific article published on 31 October 2010

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Europe PubMed Central

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15 January 2020

Ameliorative effect of flunarizine in cisplatin-induced acute renal failure via mitochondrial permeability transition pore inactivation in rats (English)

1 reference

Europe PubMed Central

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15 January 2020

Sumeet Kumar Singla

3

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15 January 2020

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Arunachalam Muthuraman

1

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15 January 2020

Shailja Sood

2

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15 January 2020

Ajay Rana

4

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15 January 2020

Atinderjeet Singh

5

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15 January 2020

Amandeep Singh

6

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15 January 2020

Jai Singh

7

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15 January 2020

publication date

31 October 2010

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15 January 2020

Naunyn-Schmiedeberg's Archives of Pharmacology

1 reference

Europe PubMed Central

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15 January 2020

383

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15 January 2020

1

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15 January 2020

57-64

1 reference

Europe PubMed Central

PubMed publication ID

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15 January 2020

https://scigraph.springernature.com/pub.10.1007/s00210-010-0572-z

0 references

Flunarizine, a calcium channel antagonist, is partially prophylactically neuroprotective in hypoxic-ischemic encephalopathy in the fetal sheep.

1 reference

https://api.crossref.org/works/10.1007%2FS00210-010-0572-Z

21 January 2018

The mitochondrial permeability transition.

1 reference

https://api.crossref.org/works/10.1007%2FS00210-010-0572-Z

21 January 2018

Effects of diallyl sulfide and diallyl disulfide on cisplatin-induced changes in glutathione and glutathione-S-transferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium determination by flame photometry; methods for serum, urine, and other fluids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin-induced nephrotoxicity is associated with oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ameliorative effect of cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on cisplatin-induced nephrotoxicity in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radical scavenging action of flunarizine in rat brain in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidant effect of calcium antagonists on microsomal membranes isolated from different brain areas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin-induced ototoxicity: the effect of pigmentation and inhibitory agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of hydroxyl radical scavenging on cisplatin-induced p53 activation, tubular cell apoptosis and nephrotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of cisplatin adducts by cellular proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin nephrotoxicity: mechanisms and renoprotective strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A long-term follow-up study of cinnarizine- and flunarizine-induced parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative stress-induced apoptosis of cochlear sensory cells: otoprotective strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action of cyclosporine on mitochondrial calcium fluxes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the mitochondrial permeability transition in cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the Mitochondrial Permeability Transition in Apoptotic and Necrotic Death After Ischemia / Reperfusion Injury to Hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose-related inversion of cinnarizine and flunarizine effects on mitochondrial permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discrimination between two steps in the mitochondrial permeability transition process

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The protective effect of royal jelly against cisplatin-induced renal oxidative stress in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ca2+ transport and oxidative damage of mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of the 21-aminosteroid U74389F on ischemia-reperfusion injury in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-n-acetyl-cysteine protection against cisplatin-induced auditory neuronal and hair cell toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cumulative toxicities from cisplatin therapy and current cytoprotective measures

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential inhibition of T-type calcium channels by neuroleptics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of T-type calcium channel blocker flunarizine on cisplatin-induced death of auditory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review of pharmacologic treatment of tinnitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin-induced apoptosis in auditory cells: role of death receptor and mitochondrial pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin nephrotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carvedilol protects against the renal mitochondrial toxicity induced by cisplatin in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium Entry Blockers in the Treatment of Vertigo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and experimental evidence for a role of calcium entry blockers in the treatment of migraine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible neuroprotective properties of flunarizine infused after asphyxia in fetal lambs are not explained by effects on cerebral blood flow or systemic blood pressure

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue sulfhydryl groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical and molecular investigations in respiratory chain deficiencies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ontogenic aspects of cisplatin-induced nephrotoxicity in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Aulosira fertilisima against cisplatin-induced nephrotoxicity and oxidative stress in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radicals and hearing. Cause, consequence, and criteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical scavenging and inhibition of lipid peroxidation by beta-blockers and by agents that interfere with calcium metabolism. A physiologically-significant process?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection from renal ischemia-reperfusion injury by the 2-methylaminochroman U83836E

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of calcium antagonists on mitochondrial swelling induced by lipid peroxidation or arachidonic acid in the rat brain in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verapamil and flunarizine protect the isolated perfused rat liver against warm ischemia and reperfusion injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flunarizine and cinnarizine inhibit mitochondrial complexes I and II: possible implication for parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-methylthiobenzoic acid protection against cisplatin nephrotoxicity: antioxidant system

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urinary nitric oxide metabolites and lipid peroxidation by-products in migraine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ethanol-induced component of 45Ca2+ uptake in PC12 cells is sensitive to Ca2+ channel modulating drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin upregulates mitochondrial nitric oxide synthase and peroxynitrite formation to promote renal injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amelioration of cisplatin-induced nephrotoxicity in rats by tetramethylpyrazine, a major constituent of the Chinese herb Ligusticum wallichi

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin nephrotoxicity: molecular mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ca(2+) channel blocker flunarizine induces caspase-10-dependent apoptosis in Jurkat T-leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statins induce calcium-dependent mitochondrial permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased activities of ubiquinol:ferricytochrome c oxidoreductase (complex III) and ferrocytochrome c:oxygen oxidoreductase (complex IV) in liver mitochondria from rats with hydroxycobalamin[c-lactam]-induced methylmalonic aciduria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of cisplatin nephrotoxicity: state of the art and recommendations from the European Society of Clinical Pharmacy Special Interest Group on Cancer Care

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agents ameliorating or augmenting the nephrotoxicity of cisplatin and other platinum compounds: a review of some recent research

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/21058009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00210-010-0572-Z

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21058009%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21058009%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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