(Q42833512)

8 November 2017

title

A cell surface tethered enzyme improves efficiency in gene-directed enzyme prodrug therapy (English)

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8 November 2017

1

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8 November 2017

Spooner RA

2

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8 November 2017

Stribbling SM

3

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8 November 2017

Light Y

4

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8 November 2017

Martin J

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8 November 2017

Springer CJ

6

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8 November 2017

publication date

1 December 1997

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8 November 2017

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8 November 2017

volume

15

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8 November 2017

issue

13

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8 November 2017

page(s)

1373-1377

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Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.

8 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Advances in cancer gene therapy

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Gene-directed enzyme prodrug therapy: a review of enzyme/prodrug combinations

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Immunotherapy for cancer by direct gene transfer into tumors

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Targeting of an inducible toxic phenotype in animal cells

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Regression of established macroscopic liver metastases after in situ transduction of a suicide gene

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Gene therapy for the treatment of brain tumors using intra-tumoral transduction with the thymidine kinase gene and intravenous ganciclovir

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Thymidine kinase-mediated killing of rat brain tumors

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Purification and properties of carboxypeptidase G2 from Pseudomonas sp. strain RS-16. Use of a novel triazine dye affinity method

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Novel prodrugs which are activated to cytotoxic alkylating agents by carboxypeptidase G2

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https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

New colorimetric cytotoxicity assay for anticancer-drug screening

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Electroporation of adherent cells in situ

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Effects of n-alcohols on junctional coupling and amylase secretion of pancreatic acinar cells

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Biodistribution of an antibody-enzyme conjugate for antibody-directed enzyme prodrug therapy in nude mice bearing a human colon adenocarcinoma xenograft

1 reference

https://api.crossref.org/works/10.1038%2FNBT1297-1373

7 January 2021

Identifiers

DOI

10.1038/NBT1297-1373

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8 November 2017

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