(Q42835550)

English

Prostacyclin inhibits platelet aggregation induced by phorbol ester or Ca2+ ionophore at steps distal to activation of protein kinase C and Ca2+-dependent protein kinases

scientific article published on February 1989

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Prostacyclin inhibits platelet aggregation induced by phorbol ester or Ca2+ ionophore at steps distal to activation of protein kinase C and Ca2+-dependent protein kinases (English)

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

platelet aggregation

1 reference

based on heuristic

inferred from title

author name string

Siess W

1

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Lapetina EG

2

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

language of work or name

0 references

publication date

1 February 1989

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

258

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

1

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

57-65

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Evidence for a role of myosin phosphorylation in the initiation of the platelet shape change response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Stimulus-response coupling in human platelets. Changes evoked by platelet-activating factor in cytoplasmic free calcium monitored with the fluorescent calcium indicator quin2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Characterization of the protein kinase activities of human platelet supernatant and particulate fractions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Regulation of contractile proteins by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Effects of the lonophore A23187 on blood platelets I. Influence on aggregation and secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Platelet activating factor raises intracellular calcium ion concentration in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Ca2+ mobilization primes protein kinase C in human platelets. Ca2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Phosphatidylinositol-specific phospholipase D: a pathway for generation of a second messenger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

cAMP reduces the affinity of Ca2+-triggered secretion in platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Differential effects of chlorpromazine on secretion, protein phosphorylation and phosphoinositide metabolism in stimulated platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Demonstration of cGMP-dependent protein kinase and cGMP-dependent phosphorylation in cell-free extracts of platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Studies and perspectives of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Inhibition of platelet-activating-factor-induced human platelet activation by prostaglandin D2. Differential sensitivity of platelet transduction processes and functional responses to inhibition by cyclic AMP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Differences in the mode of action of 1-oleoyl-2-acetyl-glycerol and phorbol ester in platelet activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

A role for Gi in control of thrombin receptor-phospholipase C coupling in human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Prostaglandin E1 and forskolin antagonize C-kinase activation in the human platelet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Effects of activation of protein kinase C on the agonist-induced stimulation and inhibition of cyclic AMP formation in intact human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

A Ca2+-and modulator-dependent myosin light chain kinase from non-muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Effects of collagen, ionophore A23187 and prostaglandin E1 on the phosphorylation of specific proteins in blood platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Regulation of the intracellular calcium level in human blood platelets: Cyclic adenosine 3′,5′-monophosphate dependent phosphorylation of a 22 000 dalton component in isolated Ca2+-accumulating vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3′,5′-cyclic monophosphate and protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Adenosine cyclic 3′,5′-monophosphate-dependent protein kinase from human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

27 May 2018

Cytoplasmic free Ca2+ in human platelets: Ca2+ thresholds and Ca-independent activation for shape-change and secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138323

16 August 2018

The inhibitory effect of cyclic AMP on phosphatidylinositol kinase is not mediated by the cAMP dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of thrombin-induced myosin phosphorylation and the assembly of cytoskeletal structures in platelets by the adenylate cyclase stimulants prostaglandin D2 and forskolin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of Ca2+ fluxes in isolated platelet vesicles: effects of cAMP-dependent protein kinase and protein kinase inhibitor on Ca2+ sequestration and release

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol esters sensitize platelets to activation by physiological agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Partial purification and characterization of thrombolamban, a 22,000 dalton cAMP-dependent protein kinase substrate in platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phospholipase D by chemotactic peptide in HL-60 granulocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytoplasmic concentration of free calcium in platelets is controlled by stimulators of cyclic AMP production (PGD2, PGE1, forskolin)

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phorbol ester-induced activation of human platelets is associated with protein kinase C phosphorylation of myosin light chains

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostacyclin inhibition of phosphatidic acid synthesis in human platelets is not mediated by protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic nucleotides control a system which regulates Ca2+ sensitivity of platelet secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rapid formation of inositol phosphates in human platelets by thrombin is inhibited by prostacyclin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular calcium fluxes in human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP inhibits platelet activation independently of its effect on cytosolic free calcium

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin endoperoxide analogues stimulate phospholipase C and protein phosphorylation during platelet shape change

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition by forskolin of cytosolic calcium rise, shape change and aggregation in quin2-loaded human platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aequorin detects increased cytoplasmic calcium in platelets stimulated with phorbol ester or diacylglycerol

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionophore A23187 stimulates phosphorylation of the 40, 000dalton protein in human platelets without phospholipase C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of human platelet myosin light chain kinase by the catalytic subunit of cyclic AMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphatidylinositol cycle and the regulation of arachidonic acid production

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that the platelet plasma membrane is impermeable to calcium and magnesium complexes of A23187. A23187-induced secretion is inhibited by MG2+ and Ca2+, and requires aggregation and active cyclooxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Counteraction of Calcium-Activated, Phospholipid-Dependent Protein Kinase Activation by Adenosine 3′,5′-Monophosphate and Guanosine 3′,5′-Monophosphate in Platelets1

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of glycoprotein Ib beta as one of the major proteins phosphorylated during exposure of intact platelets to agents that activate cyclic AMP-dependent protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/2494992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ2580057

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

ResearchGate publication ID

0 references

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