(Q42836618)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21050420%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

DRUG FOCUS: S 18986: A positive allosteric modulator of AMPA-type glutamate receptors pharmacological profile of a novel cognitive enhancer (English)

1 reference

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15 January 2020

1 reference

Katy Bernard

1

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15 January 2020

Laurence Danober

2

1 reference

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15 January 2020

Jean-Yves Thomas

3

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15 January 2020

Cécile Lebrun

4

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15 January 2020

Carmen Muñoz

5

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15 January 2020

Alex Cordi

6

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15 January 2020

Patrice Desos

7

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15 January 2020

Pierre Lestage

8

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15 January 2020

Philippe Morain

9

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15 January 2020

publication date

1 October 2010

1 reference

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CNS Neuroscience & Therapeutics

15 January 2020

published in

1 reference

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15 January 2020

volume

16

1 reference

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15 January 2020

issue

5

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15 January 2020

page(s)

e193-212

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Human memory and the cholinergic system. A relationship to aging?

15 January 2020

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2009.00088.X

Synergistic interactions between ampakines and antipsychotic drugs

21 January 2018

1 reference

12 December 2020

Miniature synaptic events maintain dendritic spines via AMPA receptor activation

1 reference

12 December 2020

Aniracetam, 1-BCP and cyclothiazide differentially modulate the function of NMDA and AMPA receptors mediating enhancement of noradrenaline release in rat hippocampal slices

1 reference

12 December 2020

Characterization of a new AMPA receptor radioligand, [3H]2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid

1 reference

12 December 2020

Hippocampal dysfunction during aging I: deficits in memory consolidation.

1 reference

12 December 2020

Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons.

1 reference

12 December 2020

Proinflammatory cytokines and interleukin-9 exacerbate excitotoxic lesions of the newborn murine neopallium

1 reference

12 December 2020

The chemokine growth-related gene product beta protects rat cerebellar granule cells from apoptotic cell death through alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors.

1 reference

12 December 2020

(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices

1 reference

12 December 2020

Effects of S 18986-1, a novel cognitive enhancer, on memory performances in an object recognition task in rats

1 reference

12 December 2020

Therapeutic potential of positive AMPA receptor modulators in the treatment of neurological disease

1 reference

12 December 2020

Modulation of learning processes by ionotropic glutamate receptor ligands.

1 reference

12 December 2020

Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator

1 reference

12 December 2020

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

1 reference

12 December 2020

Randomized, double-blind, placebo-controlled international clinical trial of the Ampakine CX516 in elderly participants with mild cognitive impairment: a progress report

1 reference

12 December 2020

An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study

1 reference

12 December 2020

Phosphorylation of the AMPA receptor GluR1 subunit is required for synaptic plasticity and retention of spatial memory

1 reference

12 December 2020

Hippocampal lesions and discrimination performance of mice in the radial maze: Sparing or impairment depending on the representational demands of the task

1 reference

12 December 2020

Positive allosteric modulators of AMPA receptors are neuroprotective against lesions induced by an NMDA agonist in neonatal mouse brain

1 reference

12 December 2020

LY503430, a novel alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor potentiator with functional, neuroprotective and neurotrophic effects in rodent models of Parkinson's disease.

1 reference

12 December 2020

Synaptic vesicle transport and synaptic membrane transporter sites in excitatory amino acid nerve terminals in Alzheimer disease

1 reference

12 December 2020

Efficacy and safety of cholinesterase inhibitors in Alzheimer's disease: a meta-analysis

1 reference

12 December 2020

A two-trial memory task with automated recording: study in young and aged rats

1 reference

12 December 2020

Attentional functions of cortical cholinergic inputs: What does it mean for learning and memory?

1 reference

12 December 2020

The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys.

1 reference

12 December 2020

S 18986, a positive modulator of AMPA receptors with cognition-enhancing properties, increases ACh release in the hippocampus of young and aged rat.

1 reference

12 December 2020

Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity

1 reference

12 December 2020

Excitatory amino acids and memory: evidence from research on Alzheimer's disease and behavioral pharmacology

1 reference

12 December 2020

Neuropharmacokinetics of a new alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) modulator, S18986 [(S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide], in the rat.

1 reference

12 December 2020

Long-term potentiation is impaired in middle-aged rats: regional specificity and reversal by adenosine receptor antagonists.

1 reference

12 December 2020

Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates

1 reference

12 December 2020

Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses.

1 reference

12 December 2020

Glutamate-based therapeutic approaches: ampakines

1 reference

12 December 2020

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers

1 reference

12 December 2020

Spatial memory deficits in middle-aged mice correlate with lower exploratory activity and a subordinate status: role of hippocampal neurotrophins

1 reference

12 December 2020

Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition

1 reference

12 December 2020

AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice.

1 reference

12 December 2020

Therapeutic potential of positive AMPA receptor modulators in the treatment of neuropsychiatric disorders

1 reference

12 December 2020

Noradrenergic and locus coeruleus modulation of the perforant path-evoked potential in rat dentate gyrus supports a role for the locus coeruleus in attentional and memorial processes

1 reference

12 December 2020

Ampakines and the threefold path to cognitive enhancement

1 reference

12 December 2020

The correlative triad among aging, dopamine, and cognition: current status and future prospects

1 reference

12 December 2020

Learning induces long-term potentiation in the hippocampus

1 reference

12 December 2020

Recent advances in positive allosteric modulators of the AMPA receptor.

1 reference

12 December 2020

Acute effects of the ampakine farampator on memory and information processing in healthy elderly volunteers

1 reference

12 December 2020

Abnormal neurotransmitter release underlying behavioral and cognitive disorders: toward concepts of dynamic and function-specific dysregulation

1 reference

12 December 2020

Microglia derived from aging mice exhibit an altered inflammatory profile.

1 reference

12 December 2020

Regulatory mechanisms of AMPA receptors in synaptic plasticity

1 reference

12 December 2020

S18986: a positive modulator of AMPA-receptors enhances (S)-AMPA-mediated BDNF mRNA and protein expression in rat primary cortical neuronal cultures

1 reference

12 December 2020

AMPA receptor potentiators as cognitive enhancers

1 reference

12 December 2020

Amyloid beta-peptide Abeta(1-42) but not Abeta(1-40) attenuates synaptic AMPA receptor function

1 reference

12 December 2020

Improvement of episodic contextual memory by S 18986 in middle-aged mice: comparison with donepezil

1 reference

12 December 2020

AMPA potentiator treatment of cognitive deficits in Alzheimer disease

1 reference

12 December 2020

AMPA receptor potentiators: application for depression and Parkinson's disease

1 reference

12 December 2020

Comparison of single vs. multiple administrations of the AMPA receptors modulator S 18986 in the object recognition task in rats

1 reference

12 December 2020

Ampakine (CX717) effects on performance and alertness during simulated night shift work

1 reference

12 December 2020

Behavioral and biological effects of chronic S18986, a positive AMPA receptor modulator, during aging

1 reference

12 December 2020

The AMPA modulator S 18986 improves declarative and working memory performances in aged mice

1 reference

12 December 2020

Modulation of social memory in male rats by neurohypophyseal peptides.

1 reference

12 December 2020

A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data

1 reference

12 December 2020

Cyclothiazide selectively potentiates AMPA- and kainate-induced [3H]norepinephrine release from rat hippocampal slices.

1 reference

12 December 2020

Cyclothiazide acts at a site on the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor complex that does not recognize competitive or noncompetitive AMPA receptor antagonists

1 reference

12 December 2020

Glutamate as a hippocampal neuron survival factor: an inherited defect in the trisomy 16 mouse

1 reference

12 December 2020

A drug that facilitates glutamatergic transmission reduces exploratory activity and improves performance in a learning-dependent task

1 reference

12 December 2020

Facilitation of glutamate receptors enhances memory

1 reference

12 December 2020

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

12 December 2020

Cortical pyramidal neurone loss may cause glutamatergic hypoactivity and cognitive impairment in Alzheimer's disease: investigative and therapeutic perspectives

1 reference

12 December 2020

Facilitation of olfactory learning by a modulator of AMPA receptors

1 reference

12 December 2020

Facilitation of glutamate receptors reverses an age-associated memory impairment in rats

1 reference

12 December 2020

Role of dorsal hippocampus in acquisition, consolidation and retrieval of rat's passive avoidance response: a tetrodotoxin functional inactivation study.

1 reference

12 December 2020

Evidence that a positive modulator of AMPA-type glutamate receptors improves delayed recall in aged humans.

1 reference

12 December 2020

Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain

1 reference

12 December 2020

Facilitative effects of the ampakine CX516 on short-term memory in rats: enhancement of delayed-nonmatch-to-sample performance.

1 reference

12 December 2020

Cyclothiazide and AMPA receptor desensitization: analyses from studies of AMPA-induced release of [3H]-noradrenaline from hippocampal slices

1 reference

12 December 2020

AMPA- and kainate-receptors differentially mediate excitatory amino acid-induced dopamine and acetylcholine release from rat striatal slices

1 reference

12 December 2020

10.1111/J.1755-5949.2009.00088.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21050420%20AND%20SRC:MED&resulttype=core&format=json

release_x3ozabw3fzat5f4s5i4tf3ku44

15 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x3ozabw3fzat5f4s5i4tf3ku44

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21050420%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

21050420

1 reference