(Q42837250)

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Microdose study of 14C-acetaminophen with accelerator mass spectrometry to examine pharmacokinetics of parent drug and metabolites in healthy subjects

scientific article published on 3 November 2010

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 November 2017

Microdose study of 14C-acetaminophen with accelerator mass spectrometry to examine pharmacokinetics of parent drug and metabolites in healthy subjects (English)

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Europe PubMed Central

PubMed publication ID

8 November 2017

pharmacokinetics

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author name string

Z Tozuka

1

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

H Kusuhara

2

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

K Nozawa

3

1 reference

Europe PubMed Central

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8 November 2017

Y Hamabe

4

1 reference

Europe PubMed Central

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8 November 2017

I Ikushima

5

1 reference

Europe PubMed Central

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8 November 2017

T Ikeda

6

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8 November 2017

Y Sugiyama

7

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8 November 2017

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publication date

3 November 2010

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8 November 2017

Clinical Pharmacology & Therapeutics

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8 November 2017

88

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8 November 2017

6

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Europe PubMed Central

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8 November 2017

824-830

1 reference

Europe PubMed Central

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8 November 2017

Evaluation of accelerator mass spectrometry in a human mass balance and pharmacokinetic study-experience with 14C-labeled (R)-6-[amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a far

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Biomedical accelerator mass spectrometry: recent applications in metabolism and pharmacokinetics

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Clinical pharmacokinetics of paracetamol

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Microdose study of a P-glycoprotein substrate, fexofenadine, using a non-radioisotope-labelled drug and LC/MS/MS.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Use of microdosing to predict pharmacokinetics at the therapeutic dose: experience with 5 drugs.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Kinetics and metabolism of paracetamol and phenacetin

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Interindividual variability in acetaminophen sulfation by human fetal liver: implications for pharmacogenetic investigations of drug-induced birth defects

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Intracellular signaling mechanisms of acetaminophen-induced liver cell death

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Acetaminophen-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Role of metabolism in drug-induced idiosyncratic hepatotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

Non-linear elimination and protein binding of probenecid

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

21 January 2018

A validation study comparing accelerator MS and liquid scintillation counting for analysis of 14C-labelled drugs in plasma, urine and faecal extracts

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

7 January 2021

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inferred from DOI database lookup

Inhibition of acetaminophen and lorazepam glucuronidation in vitro by probenecid

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

7 January 2021

based on heuristic

inferred from DOI database lookup

The effect of probenecid on paracetamol metabolism and pharmacokinetics

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

7 January 2021

based on heuristic

inferred from DOI database lookup

Microdose clinical trial: quantitative determination of fexofenadine in human plasma using liquid chromatography/electrospray ionization tandem mass spectrometry

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

7 January 2021

based on heuristic

inferred from DOI database lookup

Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.206

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/CLPT.2010.206

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 November 2017

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