(Q42864358)

English

The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons

scientific article published on 10 June 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons (English)

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

6

object named as

Gen Sobue

1 reference

Europe PubMed Central

8 November 2017

PMC publication ID

author name string

Fumika Koyano

1

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Kei Okatsu

2

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Shinsuke Ishigaki

3

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Yusuke Fujioka

4

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Mayumi Kimura

5

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Keiji Tanaka

7

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Noriyuki Matsuda

8

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Europe PubMed Central

PMC publication ID

8 November 2017

publication date

10 June 2013

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Europe PubMed Central

PMC publication ID

8 November 2017

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

18

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

8

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

672-681

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

1 reference

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27 May 2018

Regulation of A20 and other OTU deubiquitinases by reversible oxidation

1 reference

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27 May 2018

Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Deubiquitinases as a signaling target of oxidative stress

1 reference

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27 May 2018

Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mitochondrial hexokinase HKI is a novel substrate of the Parkin ubiquitin ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

The pathways of mitophagy for quality control and clearance of mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

What genetics tells us about the causes and mechanisms of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Autoregulation of Parkin activity through its ubiquitin-like domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Rotenone, paraquat, and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

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A versatile viral system for expression and depletion of proteins in mammalian cells

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27 May 2018

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

1 reference

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1 reference

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27 May 2018

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

27 May 2018

Phos-tag SDS-PAGE systems for phosphorylation profiling of proteins with a wide range of molecular masses under neutral pH conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3842116

16 August 2018

Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies

1 reference

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16 August 2018

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23751051

12 December 2020

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10.1111/GTC.12066

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 November 2017

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