(Q42867431)

English

Extensive analysis of the T315I substitution and detection of additional ABL mutations in progenitors and primitive stem cell compartment in a patient with tyrosine kinase inhibitor-resistant chronic myeloid leukemia

scientific article published on 7 October 2010

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scholarly article

1 reference

Europe PubMed Central

8 November 2017

Extensive analysis of the T315I substitution and detection of additional ABL mutations in progenitors and primitive stem cell compartment in a patient with tyrosine kinase inhibitor-resistant chronic myeloid leukemia (English)

1 reference

Europe PubMed Central

8 November 2017

chronic myeloid leukemia

0 references

author name string

Jean-Claude Chomel

1

1 reference

Europe PubMed Central

8 November 2017

Nathalie Sorel

2

1 reference

Europe PubMed Central

8 November 2017

Marie-Laure Bonnet

3

1 reference

Europe PubMed Central

8 November 2017

Angelina Bertrand

4

1 reference

Europe PubMed Central

8 November 2017

Françoise Brizard

5

1 reference

Europe PubMed Central

8 November 2017

Lydia Roy

6

1 reference

Europe PubMed Central

8 November 2017

François Guilhot

7

1 reference

Europe PubMed Central

8 November 2017

Ali G Turhan

8

1 reference

Europe PubMed Central

8 November 2017

publication date

7 October 2010

1 reference

Europe PubMed Central

8 November 2017

Leukemia & Lymphoma

1 reference

Europe PubMed Central

8 November 2017

51

1 reference

Europe PubMed Central

8 November 2017

11

1 reference

Europe PubMed Central

8 November 2017

2103-2111

1 reference

Europe PubMed Central

8 November 2017

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Overriding imatinib resistance with a novel ABL kinase inhibitor

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Therapeutic options against BCR-ABL1 T315I-positive chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Activation of tyrosine kinases by mutation of the gatekeeper threonine

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

T315I-mutated Bcr-Abl in chronic myeloid leukemia and imatinib: insights from a computational study

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

The gatekeeper mutation T315I confers resistance against small molecules by increasing or restoring the ABL-kinase activity accompanied by aberrant transphosphorylation of endogenous BCR, even in loss-of-function mutants of BCR/ABL.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Elucidating critical mechanisms of deregulated stem cell turnover in the chronic phase of chronic myeloid leukemia.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Rationale for the recommendations for harmonizing current methodology for detecting BCR-ABL transcripts in patients with chronic myeloid leukaemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Quantitative monitoring of the T315I mutation in patients with chronic myeloid leukemia (CML).

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Evidence of ABL-kinase domain mutations in highly purified primitive stem cell populations of patients with chronic myelogenous leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Detection of BCR-ABL kinase mutations in CD34+ cells from chronic myelogenous leukemia patients in complete cytogenetic remission on imatinib mesylate treatment

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

ABL single nucleotide polymorphisms may masquerade as BCR-ABL mutations associated with resistance to tyrosine kinase inhibitors in patients with chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Instability of BCR-ABL gene in primary and cultured chronic myeloid leukemia stem cells.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutations

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr-Abl-negative cells.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2010.520774

21 January 2018

Identifiers

10.3109/10428194.2010.520774

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

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