(Q42878950)

English

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

scientific article published on September 23, 2010

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Europe PubMed Central

PubMed publication ID

9 November 2017

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols (English)

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Europe PubMed Central

PubMed publication ID

9 November 2017

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lymphoblastic leukemia

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T-cell acute lymphoblastic leukemia

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Jules P Meijerink

14

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J. P P. Meijerink

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18 July 2024

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L. Zuurbier

1

0000-0002-8473-1147

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18 July 2024

I. Homminga

2

0000-0002-6794-2102

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18 July 2024

V. Calvert

3

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18 July 2024

M. L. te Winkel

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18 July 2024

J. G C A M. Buijs-Gladdines

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18 July 2024

C. Kooi

6

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18 July 2024

W. K. Smits

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18 July 2024

E. Sonneveld

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18 July 2024

A. J P. Veerman

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0000-0002-9309-301X

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18 July 2024

W. A. Kamps

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18 July 2024

M. Horstmann

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18 July 2024

E. F. Petricoin

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18 July 2024

R. Pieters

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18 July 2024

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18 July 2024

publication date

23 September 2010

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

full work available at URL

https://www.nature.com/articles/leu2010204.pdf

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20861909

18 July 2024

https://www.nature.com/articles/leu2010204.pdf

Portable Document Format

1 reference

10.1038/LEU.2010.204

https://api.crossref.org/works/10.1038/LEU.2010.204

18 July 2024

https://www.nature.com/articles/leu2010204

1 reference

10.1038/LEU.2010.204

https://api.crossref.org/works/10.1038/LEU.2010.204

18 July 2024

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

2014-2022

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

Biology and treatment of acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Treatment of acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Clinical significance of HOX11L2 expression linked to t(5;14)(q35;q32), of HOX11 expression, and of SIL-TAL fusion in childhood T-cell malignancies: results of EORTC studies 58881 and 58951

1 reference

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21 January 2018

New genetic abnormalities and treatment response in acute lymphoblastic leukemia

1 reference

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21 January 2018

Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

The tumor suppressor gene hCDC4 is frequently mutated in human T-cell acute lymphoblastic leukemia with functional consequences for Notch signaling.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Prognostic significance of molecular-cytogenetic abnormalities in pediatric T-ALL is not explained by immunophenotypic differences.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

1 reference

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21 January 2018

BFM-oriented treatment for children with acute lymphoblastic leukemia without cranial irradiation and treatment reduction for standard risk patients: results of DCLSG protocol ALL-8 (1991-1996).

1 reference

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21 January 2018

Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004).

1 reference

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21 January 2018

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia

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The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

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More powerful procedures for multiple significance testing

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Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

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https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Mutational analysis of the hCDC4 gene in gastric carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Structure of the Notch1-negative regulatory region: implications for normal activation and pathogenic signaling in T-ALL

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

CALM-AF10 is a common fusion transcript in T-ALL and is specific to the TCRgammadelta lineage.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

NOTCH1 mutation can be an early, prenatal genetic event in T-ALL.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Gamma-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2010.204

21 January 2018

Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia

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CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

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A second NOTCH1 chromosome rearrangement: t(9;14)(q34.3;q11.2) in T-cell neoplasia

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The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia

1 reference

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Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia

1 reference

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7 January 2021

based on heuristic

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24

91

1212

author name string

M van Grotel

publication date

2006

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Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection

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10.1038/LEU.2010.204

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Prognostic Significance of NOTCH1 and FBXW7 Mutations in Childhood T-Cell Acute Lymphoblastic Leukemia (T-ALL): Results From the EORTC Children Leukemia Group.

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The Favorable Effect of Activating NOTCH1 Receptor Mutations On Long Term Outcome in T-ALL Is Treatment Related and Can Be Separated From NOTCH Pathway Activation by FBXW7 Loss of Function.

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10.1038/LEU.2010.204

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 November 2017

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