(Q42917454)

11 November 2017

title

Opa1 deficiency in a mouse model of dominant optic atrophy leads to retinal ganglion cell dendropathy (English)

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11 November 2017

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retinal ganglion cell

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3

Marcela Votruba

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11 November 2017

Pete A Williams

1

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11 November 2017

James E Morgan

series ordinal

2

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11 November 2017

language of work or name

English

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publication date

3 September 2010

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11 November 2017

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11 November 2017

volume

133

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11 November 2017

issue

10

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11 November 2017

page(s)

2942-2951

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Developmental expression profile of the optic atrophy gene product: OPA1 is not localized exclusively in the mammalian retinal ganglion cell layer

11 November 2017

cites work

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https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy.

21 January 2018

1 reference

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes

21 January 2018

1 reference

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Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

Electrophysiology and colour perimetry in dominant infantile optic atrophy

21 January 2018

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Mitochondrial optic neuropathies: how two genomes may kill the same cell type?

21 January 2018

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Optic nerve degeneration and mitochondrial dysfunction: genetic and acquired optic neuropathies

21 January 2018

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Disruption of fusion results in mitochondrial heterogeneity and dysfunction

21 January 2018

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Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

21 January 2018

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Mitochondrial fusion protects against neurodegeneration in the cerebellum.

21 January 2018

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Cyclosporine A for neuroprotection: establishing dosing guidelines for safe and effective use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

eOPA1: an online database for OPA1 mutations

21 January 2018

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A fast and accurate procedure for deriving the Sholl profile in quantitative studies of neuronal morphology

21 January 2018

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Resveratrol and rapamycin: are they anti-aging drugs?

21 January 2018

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The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals

21 January 2018

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Treatment of mitochondrial electron transport chain disorders: a review of clinical trials over the past decade

21 January 2018

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The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

21 January 2018

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Ageing and neuronal vulnerability

21 January 2018

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Coenzyme Q10 protects retinal cells against oxidative stress in vitro and in vivo

21 January 2018

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Bipolar cells of the mouse retina: a gene gun, morphological study

21 January 2018

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Neuroprotective effects of minocycline against in vitro and in vivo retinal ganglion cell damage

21 January 2018

1 reference

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Large-scale morphological survey of mouse retinal ganglion cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production.

21 January 2018

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Quality control of mitochondria: protection against neurodegeneration and ageing

21 January 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

21 January 2018

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A lethal defect of mitochondrial and peroxisomal fission

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

OPA1 deficiency associated with increased autophagy in retinal ganglion cells in a murine model of dominant optic atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

Retinal ganglion cell dendrites undergo a visual activity-dependent redistribution after eye opening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

The molecular mechanisms of OPA1-mediated optic atrophy in Drosophila model and prospects for antioxidant treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

Optic neuropathies--importance of spatial distribution of mitochondria as well as function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWQ218

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWQ218

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11 November 2017

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