(Q42917978)

English

Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies.

scientific article published on 15 December 2009

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scholarly article

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15 January 2020

Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies (English)

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15 January 2020

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15 January 2020

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15 January 2020

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15 January 2020

Jack-Ansgar Bruun

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15 January 2020

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Serhiy Pankiv

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15 January 2020

Aud Øvervatn

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15 January 2020

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15 December 2009

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15 January 2020

Journal of Biological Chemistry

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15 January 2020

285

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15 January 2020

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15 January 2020

5941-5953

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15 January 2020

Autophagy suppresses tumorigenesis through elimination of p62

1 reference

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27 May 2018

A role for ubiquitin in selective autophagy

1 reference

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27 May 2018

Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling

1 reference

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A role for NBR1 in autophagosomal degradation of ubiquitinated substrates

1 reference

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27 May 2018

Structural basis for sorting mechanism of p62 in selective autophagy

1 reference

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27 May 2018

The signaling adaptor p62 is an important NF-kappaB mediator in tumorigenesis

1 reference

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27 May 2018

Nuclear polyglutamine-containing protein aggregates as active proteolytic centers

1 reference

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27 May 2018

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport

1 reference

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27 May 2018

Polyglutamine diseases: emerging concepts in pathogenesis and therapy

1 reference

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27 May 2018

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Structural biology of nucleocytoplasmic transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Phosphatidylinositol 3-kinase/Akt signaling enhances nuclear localization and transcriptional activity of BRCA1

1 reference

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27 May 2018

Nucleus-vacuole junctions and piecemeal microautophagy of the nucleus in S. cerevisiae

1 reference

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27 May 2018

Classical nuclear localization signals: definition, function, and interaction with importin alpha

1 reference

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27 May 2018

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

1 reference

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27 May 2018

ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy

1 reference

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27 May 2018

PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins

1 reference

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27 May 2018

Phosphoproteome analysis of the human mitotic spindle

1 reference

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27 May 2018

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

1 reference

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27 May 2018

Nuclear import of Epstein-Barr virus nuclear antigen 1 mediated by NPI-1 (Importin alpha5) is up- and down-regulated by phosphorylation of the nuclear localization signal for which Lys379 and Arg380 are essential

1 reference

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27 May 2018

Cytosolic overexpression of p62 sequestosome 1 in neoplastic prostate tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Leucine-rich nuclear-export signals: born to be weak

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

NESbase version 1.0: a database of nuclear export signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Clastosome: a subtype of nuclear body enriched in 19S and 20S proteasomes, ubiquitin, and protein substrates of proteasome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Delineation of mRNA export pathways by the use of cell-permeable peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

1 reference

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27 May 2018

Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

p62 functions as a p38 MAP kinase regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear export

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

1 reference

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27 May 2018

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

1 reference

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27 May 2018

Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

27 May 2018

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

1 reference

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27 May 2018

The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs

1 reference

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27 May 2018

A nuclear export sequence located on a beta-strand in fibroblast growth factor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820819

16 August 2018

The ubiquitin-binding protein p62 is expressed in breast cancers showing features of aggressive disease

1 reference

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16 August 2018

Diverse polyubiquitin interaction properties of ubiquitin-associated domains

1 reference

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16 August 2018

Morphogenesis of Lewy bodies: dissimilar incorporation of alpha-synuclein, ubiquitin, and p62.

1 reference

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16 August 2018

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

1 reference

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16 August 2018

NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

1 reference

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21 January 2018

Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease

1 reference

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21 January 2018

A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals

1 reference

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12 December 2020

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Ubiquitin/proteasome-mediated degradation of p19INK4d determines its periodic expression during the cell cycle

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Low micromolar levels of hydrogen peroxide and proteasome inhibitors induce the 60-kDa A170 stress protein in murine peritoneal macrophages

1 reference

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12 December 2020

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Phosphorylation of A170 stress protein by casein kinase II-like activity in macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteasomes degrade proteins in focal subdomains of the human cell nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of p62/SQSTM1 antibodies for neuropathological diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018885

12 December 2020

based on heuristic

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Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions visualized with ubiquitin-binding protein p62 immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20018885

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.039925

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018885%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018885%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20018885%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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