(Q42922896)

11 November 2017

title

PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy (English)

1 reference

11 November 2017

1

1 reference

11 November 2017

4

1 reference

11 November 2017

8

1 reference

11 November 2017

10

1 reference

11 November 2017

15

1 reference

11 November 2017

M Porru

3

0 references

Carlo Leonetti

object named as

C Leonetti

14

0 references

author name string

M Scarsella

2

1 reference

11 November 2017

S Iachettini

5

1 reference

11 November 2017

L Tentori

6

1 reference

11 November 2017

G Graziani

7

1 reference

11 November 2017

M F G Stevens

9

1 reference

11 November 2017

D Passeri

11

1 reference

11 November 2017

E Gilson

12

1 reference

11 November 2017

G Zupi

13

1 reference

11 November 2017

language of work or name

English

0 references

publication date

30 August 2010

1 reference

11 November 2017

1 reference

11 November 2017

volume

29

1 reference

11 November 2017

issue

47

1 reference

11 November 2017

page(s)

6280-6293

1 reference

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

11 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

TRF2 inhibition promotes anchorage-independent growth of telomerase-positive human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Detection of poly(ADP-ribose) polymerase activation in oxidatively stressed cells and tissues using biotinylated NAD substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

The role of the poly(ADP-ribose) polymerase tankyrase1 in telomere length control by the TRF1 component of the shelterin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Antitumor polycyclic acridines. 8.(1) Synthesis and telomerase-inhibitory activity of methylated pentacyclic acridinium salts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Targeting the limitless replicative potential of cancer: the telomerase/telomere pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Targeted therapy for cancer using PARP inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

The role of poly(ADP-ribose) in the DNA damage signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Increased melanoma growth and metastasis spreading in mice overexpressing placenta growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Physiological relevance of telomeric G-quadruplex formation: a potential drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Stem cell marker expression and proliferation and apoptosis of vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Targeting poly(ADP-ribose) polymerase: a two-armed strategy for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Preclinical profile of antitumor activity of a novel hydrophilic camptothecin, ST1968.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Functional characterization of the poly(ADP-ribose) polymerase activity of tankyrase 1, a potential regulator of telomere length

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

PARP-1 ensures regulation of replication fork progression by homologous recombination on damaged DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

DNA damage foci at dysfunctional telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Chemopotentiation by PARP inhibitors in cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Normal human chromosomes have long G-rich telomeric overhangs at one end

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Reconstitution of hTERT restores tumorigenicity in melanoma-derived c-Myc low-expressing clones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Poly(ADP-ribose) binds to specific domains in DNA damage checkpoint proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.344

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.344

1 reference

Dimensions Publication ID

11 November 2017

1037313551

0 references

1 reference