(Q42925784)

11 November 2017

title

Human pregnane X receptor agonism by Ginkgo biloba extract: assessment of the role of individual ginkgolides (English)

1 reference

11 November 2017

Human Pregnane X Receptor Agonism by Ginkgo biloba Extract: Assessment of the Role of Individual Ginkgolides (English)

1 reference

https://api.crossref.org/works/10.1124/JPET.110.172338

23 June 2024

0 references

Aik Jiang Lau

1

1 reference

11 November 2017

Guixiang Yang

2

1 reference

11 November 2017

Ganesh Rajaraman

3

1 reference

11 November 2017

Christie C. Baucom

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739453

23 June 2024

Thomas K. H. Chang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739453

23 June 2024

language of work or name

English

0 references

publication date

25 August 2010

1 reference

full work available at URL

11 November 2017

http://intl-jpet.aspetjournals.org/cgi/content/abstract/335/3/771

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20739453

https://syndication.highwire.org/content/doi/10.1124/jpet.110.172338

23 June 2024

1 reference

https://api.crossref.org/works/10.1124/JPET.110.172338

Journal of Pharmacology and Experimental Therapeutics

23 June 2024

published in

1 reference

11 November 2017

volume

335

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11 November 2017

issue

3

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11 November 2017

page(s)

771-780

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An update on drug interactions with the herbal medicine Ginkgo biloba

11 November 2017

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Dissection of the LXXLL nuclear receptor-coactivator interaction motif using combinatorial peptide libraries: discovery of peptide antagonists of estrogen receptors alpha and beta

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Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels

23 June 2024

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Distinct role of bilobalide and ginkgolide A in the modulation of rat CYP2B1 and CYP3A23 gene expression by Ginkgo biloba extract in cultured hepatocytes

23 June 2024

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23 June 2024

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23 June 2024

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Induction of cytochrome P450 3A by the Ginkgo biloba extract and bilobalides in human and rat primary hepatocytes

23 June 2024

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A pharmacophore for human pregnane X receptor ligands

23 June 2024

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Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers

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The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

23 June 2024

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Pharmaceutical quality of different Ginkgo biloba brands

23 June 2024

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Inhibition of human CYP2B6-catalyzed bupropion hydroxylation by Ginkgo biloba extract: effect of terpene trilactones and flavonols

23 June 2024

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Isolation and culture of primary human hepatocytes

23 June 2024

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

23 June 2024

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Bioactive terpenoids and flavonoids from Ginkgo biloba extract induce the expression of hepatic drug-metabolizing enzymes through pregnane X receptor, constitutive androstane receptor, and aryl hydrocarbon receptor-mediated pathways

23 June 2024

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T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR

23 June 2024

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St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor

23 June 2024

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Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands

23 June 2024

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Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators

23 June 2024

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Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.

23 June 2024

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Gene expression of HIF-1alpha and XRCC4 measured in human samples by real-time RT-PCR using the sigmoidal curve-fitting method

23 June 2024

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Ginkgolide A contributes to the potentiation of acetaminophen toxicity by Ginkgo biloba extract in primary cultures of rat hepatocytes

23 June 2024

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Modulation of CYP1B1 and CYP1A1 gene expression and activation of aryl hydrocarbon receptor by Ginkgo biloba extract in MCF-10A human mammary epithelial cells

23 June 2024

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Activation of pregnane X receptor and induction of MDR1 by dietary phytochemicals

23 June 2024

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Feeding of Ginkgo biloba extract (GBE) enhances gene expression of hepatic cytochrome P-450 and attenuates the hypotensive effect of nicardipine in rats

23 June 2024

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23 June 2024

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The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

23 June 2024

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CAR and PXR: the xenobiotic-sensing receptors

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Identification of amino acids in rat pregnane X receptor that determine species-specific activation

23 June 2024

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Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers

23 June 2024

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Chemical analysis and quality control of Ginkgo biloba leaves, extracts, and phytopharmaceuticals

23 June 2024

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Effects of Ginkgo biloba in dementia: systematic review and meta-analysis

23 June 2024

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St John's wort, a herbal antidepressant, activates the steroid X receptor.

23 June 2024

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Identification of Ginkgo biloba as a novel activator of pregnane X receptor

23 June 2024

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The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism

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23 June 2024

Identifiers

1 reference

11 November 2017

1 reference