(Q42932713)

11 November 2017

title

Cloning, overexpression and characterization of Leishmania donovani squalene synthase (English)

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11 November 2017

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ChEBI release 2020-05-28

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Leishmania donovani

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1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20722739

19 June 2024

gene expression

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20722739

19 June 2024

author name string

Prachi Bhargava

1

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11 November 2017

Kishore Kumar

2

1 reference

11 November 2017

Uma Roy

5

1 reference

11 November 2017

Shailendra S. Chaudhaery

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20722739

19 June 2024

Anil K. Saxena

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20722739

19 June 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20722739

19 June 2024

publication date

16 August 2010

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full work available at URL

11 November 2017

published in

FEMS Microbiology Letters

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11 November 2017

volume

311

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11 November 2017

issue

1

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11 November 2017

page(s)

82-92

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Solubilization and partial purification of squalene synthase from daffodil microsomal membranes

11 November 2017

cites work

1

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

19 June 2024

zaragozic acid

2

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Discovery, biosynthesis, and mechanism of action of the zaragozic acids: potent inhibitors of squalene synthase

19 June 2024

3

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Conserved linkage groups associated with large-scale chromosomal rearrangements between Old World and New World Leishmania genomes

19 June 2024

4

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Quinuclidine derivatives as potential antiparasitics

19 June 2024

5

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Isolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection.

19 June 2024

6

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Molecular characterization of tobacco squalene synthase and regulation in response to fungal elicitor

19 June 2024

8

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Isolation and primary structure of the ERG9 gene of Saccharomyces cerevisiae encoding squalene synthetase

19 June 2024

9

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Molecular cloning, in vitro expression and characterization of a plant squalene synthetase cDNA.

19 June 2024

12

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

cDNA cloning of squalene synthase genes from mono- and dicotyledonous plants, and expression of the gene in rice

19 June 2024

13

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

19 June 2024

Leishmaniasis

14

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Molecular cloning and functional expression of a cDNA for mouse squalene synthase

19 June 2024

15

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Molecular cloning and characterization of the yeast gene for squalene synthetase

19 June 2024

16

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Cloning, solubilization, and characterization of squalene synthase from Thermosynechococcus elongatus BP-1

19 June 2024

19

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Inhibition of mammalian squalene synthetase activity by zaragozic acid A is a result of competitive inhibition followed by mechanism-based irreversible inactivation

19 June 2024

20

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Overexpression, purification, and kinetic characterization of a carboxyl-terminal-truncated yeast squalene synthetase.

19 June 2024

21

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa

19 June 2024

22

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Cloning, expression, and characterization of cDNAs encoding Arabidopsis thaliana squalene synthase

19 June 2024

26

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

19 June 2024

27

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme.

19 June 2024

28

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Expression of cysteine proteinase type I and II of Leishmania infantum and their recognition by sera during canine and human visceral leishmaniasis

19 June 2024

30

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

High conservation of the fine-scale organisation of chromosome 5 between two pathogenic Leishmania species.

19 June 2024

31

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Antiproliferative and ultrastructural effects of BPQ-OH, a specific inhibitor of squalene synthase, on Leishmania amazonensis.

19 June 2024

32

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo

19 June 2024

35

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Squalene synthase as a chemotherapeutic target in Trypanosoma cruzi and Leishmania mexicana

19 June 2024

37

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

In vitro and in vivo activities of E5700 and ER-119884, two novel orally active squalene synthase inhibitors, against Trypanosoma cruzi

19 June 2024

38

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Molecular and functional characterization of adenylate kinase 2 gene from Leishmania donovani.

19 June 2024

39

1 reference

https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

Squalene synthase inhibitors

19 June 2024

40

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https://api.crossref.org/works/10.1111/J.1574-6968.2010.02071.X

19 June 2024

Identifiers

1 reference

11 November 2017

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