(Q42932963)

11 November 2017

title

The proteasome inhibitor bortezomib drastically affects inflammation and bone disease in adjuvant-induced arthritis in rats (English)

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11 November 2017

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Achilles Anagnostopoulos

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Achilles Anagnostopoulos

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author name string

Evangelia Yannaki

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11 November 2017

Anastasia Papadopoulou

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Evangelia Athanasiou

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Panayotis Kaloyannidis

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Argyro Paraskeva

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Dimitris Bougiouklis

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Panayotis Palladas

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Minas Yiangou

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publication date

1 November 2010

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11 November 2017

published in

Arthritis & Rheumatology

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11 November 2017

volume

62

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11 November 2017

issue

11

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11 November 2017

page(s)

3277-3288

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Development of the proteasome inhibitor Velcade (Bortezomib).

11 November 2017

cites work

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Proteasome inhibitor bortezomib for the treatment of multiple myeloma.

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A phase 2 study of bortezomib in relapsed, refractory myeloma

21 January 2018

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Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-κB-dependent process

21 January 2018

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Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib

21 January 2018

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The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

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Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

21 January 2018

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Diverse agents act at multiple levels to inhibit the Rel/NF-kappaB signal transduction pathway

21 January 2018

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Cytokine pathways and joint inflammation in rheumatoid arthritis

21 January 2018

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Increased synovial tissue NF-kappa B1 expression at sites adjacent to the cartilage-pannus junction in rheumatoid arthritis

21 January 2018

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Distinct roles for the NF-kappaB1 (p50) and c-Rel transcription factors in inflammatory arthritis

21 January 2018

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Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

21 January 2018

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Chronic exposure to tumor necrosis factor (TNF) in vitro impairs the activation of T cells through the T cell receptor/CD3 complex; reversal in vivo by anti-TNF antibodies in patients with rheumatoid arthritis

21 January 2018

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Altered lymphocyte reactivity in rheumatoid arthritis

21 January 2018

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Fibroblast biology. Role of synovial fibroblasts in the pathogenesis of rheumatoid arthritis

21 January 2018

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Long term treatment of rheumatoid arthritis with rituximab

21 January 2018

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IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial

21 January 2018

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21 January 2018

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Evidence for differential acquired drug resistance to anti-tumour necrosis factor agents in rheumatoid arthritis.

21 January 2018

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Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials

21 January 2018

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Role of the proteasome and NF-kappaB in streptococcal cell wall-induced polyarthritis

21 January 2018

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Bortezomib attenuates murine collagen-induced arthritis

21 January 2018

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Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining

21 January 2018

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Autoimmune disease. a problem of defective apoptosis

21 January 2018

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Bortezomib induces selective depletion of alloreactive T lymphocytes and decreases the production of Th1 cytokines

21 January 2018

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Myeloma bone disease and proteasome inhibition therapies.

21 January 2018

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Inhibition of osteoblastic bone formation by nuclear factor-kappaB.

21 January 2018

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Pathogen recognition and innate immunity

21 January 2018

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The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages

21 January 2018

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Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis.

21 January 2018

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Expression and regulation of Toll-like receptor 2 in rheumatoid arthritis synovium

21 January 2018

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Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

21 January 2018

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Evolving concepts of rheumatoid arthritis

21 January 2018

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An essential role of NF-kappaB in the "tumor-like" phenotype of arthritic synoviocytes

21 January 2018

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NF-kappaB regulation in the immune system

21 January 2018

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Safety of prolonged therapy with bortezomib in relapsed or refractory multiple myeloma

21 January 2018

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Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.27690

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11 November 2017

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