(Q42944154)

1 July 2019

title

Eicosapentaenoic acid improves hepatic steatosis independent of PPARα activation through inhibition of SREBP-1 maturation in mice (English)

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1 July 2019

1 reference

8

Eiji Tanaka

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1 July 2019

Frank J. Gonzalez

9

object named as

Frank J. Gonzalez

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691165

18 June 2024

author name string

Naoki Tanaka

1

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1 July 2019

Xiuguo Zhang

2

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1 July 2019

Eiko Sugiyama

3

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1 July 2019

Hiroyuki Kono

4

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1 July 2019

Akira Horiuchi

5

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1 July 2019

Takero Nakajima

6

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1 July 2019

Hiroki Kanbe

7

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1 July 2019

Toshifumi Aoyama

10

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1 July 2019

language of work or name

English

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publication date

4 August 2010

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1 July 2019

full work available at URL

https://europepmc.org/articles/pmc6338080?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691165

https://europepmc.org/articles/PMC6338080

18 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691165

https://europepmc.org/articles/PMC6338080?pdf=render

18 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691165

https://doi.org/10.1016/j.bcp.2010.07.031

18 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20691165

https://api.elsevier.com/content/article/PII:S0006295210005691?httpAccept=text/xml

18 June 2024

1 reference

10.1016/J.BCP.2010.07.031

Crossref

DOI

https://api.crossref.org/works/10.1016/J.BCP.2010.07.031

https://api.elsevier.com/content/article/PII:S0006295210005691?httpAccept=text/plain

18 June 2024

1 reference

10.1016/J.BCP.2010.07.031

Crossref

DOI

https://api.crossref.org/works/10.1016/J.BCP.2010.07.031

18 June 2024

published in

Biochemical Pharmacology

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1 July 2019

volume

80

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1 July 2019

issue

10

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1 July 2019

page(s)

1601-1612

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1 July 2019

Fish oil feeding decreases mature sterol regulatory element-binding protein 1 (SREBP-1) by down-regulation of SREBP-1c mRNA in mouse liver. A possible mechanism for down-regulation of lipogenic enzyme mRNAs

cites work

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12 December 2020

Genomic structure and chromosomal mapping of the human site-1 protease (S1P) gene

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Peroxisome proliferator-activated receptor alpha is not rate-limiting for the lipoprotein-lowering action of fish oil.

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Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription

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Polyunsaturated fatty acids suppress sterol regulatory element-binding protein 1c promoter activity by inhibition of liver X receptor (LXR) binding to LXR response elements

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12 December 2020

Fish oil feeding alters liver gene expressions to defend against PPARalpha activation and ROS production

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Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPAR alpha

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Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

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n-3 Polyunsaturated fatty acids, fatal ischemic heart disease, and nonfatal myocardial infarction in older adults: the Cardiovascular Health Study

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In vivo stabilization of nuclear retinoid X receptor alpha in the presence of peroxisome proliferator-activated receptor alpha

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Unsaturated fatty acid regulation of peroxisome proliferator-activated receptor alpha activity in rat primary hepatocytes

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A simple method for the isolation and purification of total lipides from animal tissues

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Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression

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Molecular mediators of hepatic steatosis and liver injury

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Peroxisome proliferator-activated receptor alpha protects against alcohol-induced liver damage

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Nonalcoholic fatty liver disease: from steatosis to cirrhosis

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PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

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Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study.

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A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury.

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Long-term follow-up of patients with NAFLD and elevated liver enzymes

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Novel n-3 fatty acid oxidation products activate Nrf2 by destabilizing the association between Keap1 and Cullin3.

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12 December 2020

SREBP-1c transcription factor and lipid homeostasis: clinical perspective

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12 December 2020

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

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12 December 2020

Hepatitis C virus core protein induces spontaneous and persistent activation of peroxisome proliferator-activated receptor alpha in transgenic mice: implications for HCV-associated hepatocarcinogenesis

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PPARalpha: mechanism of species differences and hepatocarcinogenesis of peroxisome proliferators

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Nutritional assessment and hepatic fatty acid composition in non-alcoholic fatty liver disease (NAFLD): a cross-sectional study.

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PPARalpha activation is essential for HCV core protein-induced hepatic steatosis and hepatocellular carcinoma in mice

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12 December 2020

Highly purified eicosapentaenoic acid treatment improves nonalcoholic steatohepatitis

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12 December 2020

Non-alcoholic fatty liver disease: the mist gradually clears

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Gene expression in human NAFLD.

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12 December 2020

Cholesterol-lowering effect of bezafibrate is independent of peroxisome proliferator-activated receptor activation in mice

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12 December 2020

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

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12 December 2020

Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management

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12 December 2020

Bezafibrate at clinically relevant doses decreases serum/liver triglycerides via down-regulation of sterol regulatory element-binding protein-1c in mice: a novel peroxisome proliferator-activated receptor alpha-independent mechanism

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12 December 2020

Eicosapentaenoic acid ameliorates steatohepatitis and hepatocellular carcinoma in hepatocyte-specific Pten-deficient mice

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12 December 2020

Polyenephosphatidylcholine prevents alcoholic liver disease in PPARalpha-null mice through attenuation of increases in oxidative stress

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12 December 2020

Development from simple steatosis to liver cirrhosis and hepatocellular carcinoma: a 27-year follow-up case.

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12 December 2020

Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver. cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of [...]

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12 December 2020

The inverse relation between fish consumption and 20-year mortality from coronary heart disease

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12 December 2020

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

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12 December 2020

Purification of human very-long-chain acyl-coenzyme A dehydrogenase and characterization of its deficiency in seven patients

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12 December 2020

A novel disease with deficiency of mitochondrial very-long-chain acyl-CoA dehydrogenase

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12 December 2020

Haemostatic function and platelet polyunsaturated fatty acids in Eskimos

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12 December 2020

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

1 reference

12 December 2020

Polyunsaturated fatty acid suppression of hepatic fatty acid synthase and S14 gene expression does not require peroxisome proliferator-activated receptor alpha

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12 December 2020

Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha)

1 reference

12 December 2020

Fatty acid binding protein isoforms: structure and function

1 reference

12 December 2020

10.1016/J.BCP.2010.07.031

Identifiers

DOI

1 reference

1 July 2019

PMC publication ID

6338080

1 reference

1 July 2019

1 reference

1 July 2019