(Q42945318)

11 November 2017

title

Dimethylcelecoxib inhibits mPGES-1 promoter activity by influencing EGR1 and NF-κB (English)

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

17 June 2024

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20688046

Manfred Schubert-Zsilavecz

17 June 2024

author

4

object named as

Manfred Schubert-Zsilavecz

1 reference

11 November 2017

Klaus Deckmann

1

1 reference

11 November 2017

Florian Rörsch

2

1 reference

11 November 2017

Ramona Steri

3

1 reference

11 November 2017

Gerd Geisslinger

5

1 reference

11 November 2017

Sabine Grösch

6

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11 November 2017

language of work or name

English

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publication date

3 August 2010

1 reference

full work available at URL

11 November 2017

https://hal.archives-ouvertes.fr/hal-00623304/file/PEER_stage2_10.1016%252Fj.bcp.2010.07.032.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20688046

https://api.elsevier.com/content/article/PII:S0006295210005708?httpAccept=text/xml

17 June 2024

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

https://api.elsevier.com/content/article/PII:S0006295210005708?httpAccept=text/plain

17 June 2024

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

17 June 2024

published in

Biochemical Pharmacology

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11 November 2017

volume

80

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11 November 2017

issue

9

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11 November 2017

page(s)

1365-1372

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Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1.

11 November 2017

cites work

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1074/JBC.M312972200

Dimethylcelecoxib inhibits prostaglandin E2 production

1

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

17 June 2024

2

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2.

17 June 2024

3

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

The molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2,3-dimethylphenylamino)pyrimidin-2-ylthio)octanoic acid (YS121), a dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase

17 June 2024

4

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Nonacidic inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1) identified by a multistep virtual screening protocol

17 June 2024

5

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression

17 June 2024

6

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Human glutathione dependent prostaglandin E synthase: gene structure and regulation

17 June 2024

7

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Basal expression of the human MAPEG members microsomal glutathione transferase 1 and prostaglandin E synthase genes is mediated by Sp1 and Sp3.

17 June 2024

8

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.

17 June 2024

9

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase.

17 June 2024

10

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

mPGES-1 as a novel target for arthritis

17 June 2024

11

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https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Determination of etoricoxib in human plasma by liquid chromatography–tandem mass spectrometry with electrospray ionisation

17 June 2024

12

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Interleukin-1beta induces chronic activation and de novo synthesis of neutral ceramidase in renal mesangial cells

17 June 2024

13

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells

17 June 2024

14

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion.

17 June 2024

15

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells

17 June 2024

16

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Antitumor properties of dimethyl-celecoxib, a derivative of celecoxib that does not inhibit cyclooxygenase-2: implications for glioma therapy

17 June 2024

17

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Effects of prostaglandin D(2) and 5-lipoxygenase products on the expression of CD203c and CD11b by basophils.

17 June 2024

18

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

HDAC4 contributes to IL-1-induced mPGES-1 expression in human synovial fibroblasts through up-regulation of Egr-1 transcriptional activity

17 June 2024

20

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Analysis of functional elements in the human Egr-1 gene promoter.

17 June 2024

21

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription

17 June 2024

22

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib

17 June 2024

23

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

The nuclear signaling of NF-kappaB: current knowledge, new insights, and future perspectives

17 June 2024

24

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https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

PPARgamma inhibition of cyclooxygenase-2, PGE2 synthase, and inducible nitric oxide synthase in cardiac myocytes

17 June 2024

25

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Peroxisome proliferator-activated receptor gamma as a molecular target of resveratrol-induced modulation of polyamine metabolism

17 June 2024

26

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) activation suppresses ischemic induction of Egr-1 and its inflammatory gene targets

17 June 2024

27

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.07.032

17 June 2024

Identifiers

1 reference

11 November 2017

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