(Q42945648)

11 November 2017

title

18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial (English)

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11 November 2017

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phase II clinical trial

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flutemetamol F-18

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mild cognitive impairment

ChEBI release 2020-05-28

ChEBI ID

76611

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cognitive dysfunction

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1

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7

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19

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Christine Bastin

5

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Gaëtan Garraux

Gaëtan Garraux

12

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Ian Law

Ian Law

8

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Eric Salmon

Eric Salmon

4

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Lennart Minthon

11

Lennart Minthon

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14

Guy Bormans

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2

Koen Van Laere

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3

Adrian Ivanoiu

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6

Eric Triau

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9

Allan Andersen

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13

Natalie Nelissen

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Alex Korner

10

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Chris Buckley

15

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Rikard Owenius

16

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Lennart Thurfjell

17

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Gill Farrar

18

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publication date

1 September 2010

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volume

68

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issue

3

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11 November 2017

page(s)

319-329

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Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

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cites work

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Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease

21 January 2018

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Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh Compound B.

21 January 2018

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In vitro characterization of Pittsburgh compound-B binding to Lewy bodies.

21 January 2018

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Abeta amyloid deposition in the language system and how the brain responds

21 January 2018

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Imaging beta-amyloid burden in aging and dementia.

21 January 2018

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Imaging of amyloid burden and distribution in cerebral amyloid angiopathy.

21 January 2018

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Abeta amyloid and glucose metabolism in three variants of primary progressive aphasia

21 January 2018

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Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography.

21 January 2018

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Amyloid imaging in mild cognitive impairment subtypes.

21 January 2018

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Beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease

21 January 2018

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Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

21 January 2018

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APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging

21 January 2018

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PET of brain amyloid and tau in mild cognitive impairment.

21 January 2018

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Detection of Alzheimer pathology in vivo using both 11C-PIB and 18F-FDDNP PET.

21 January 2018

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Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism

21 January 2018

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Whole-body biodistribution and radiation dosimetry of 18F-GE067: a radioligand for in vivo brain amyloid imaging

21 January 2018

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Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease.

21 January 2018

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Mild cognitive impairment: clinical characterization and outcome

21 January 2018

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Consideration of optimal time window for Pittsburgh compound B PET summed uptake measurements

21 January 2018

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Implementation and validation of a fully automatic system for intra- and interindividual registration of PET brain scans.

21 January 2018

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Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain

21 January 2018

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Impact of Alzheimer's pathology on cognitive trajectories in nondemented elderly

21 January 2018

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Characterization of PiB binding to white matter in Alzheimer disease and other dementias

21 January 2018

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Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

21 January 2018

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11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANA.22068

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11 November 2017

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