(Q42945852)

11 November 2017

title

Quantification of apixaban's therapeutic utility in prevention of venous thromboembolism: selection of phase III trial dose (English)

1 reference

11 November 2017

main subject

phase III clinical trial

0 references

apixaban

1 reference

inferred from title

venous thromboembolism

1 reference

modelling biological systems

inferred from title

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686477

17 June 2024

6

M. Pfister

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686477

17 June 2024

T. A. Leil

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686477

17 June 2024

Y. Feng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686477

17 June 2024

L. Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686477

17 June 2024

A. Paccaly

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686477

17 June 2024

P. Mohan

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20686477

17 June 2024

language of work or name

English

0 references

publication date

4 August 2010

1 reference

Clinical Pharmacology & Therapeutics

11 November 2017

published in

1 reference

11 November 2017

volume

88

1 reference

11 November 2017

issue

3

1 reference

11 November 2017

page(s)

375-382

1 reference

Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

11 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Novel factor Xa inhibitors for prevention and treatment of thromboembolic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Apixaban metabolism and pharmacokinetics after oral administration to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Concepts and challenges in quantitative pharmacology and model-based drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Optimizing dose selection with modeling and simulation: application to the vasopeptidase inhibitor M100240.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Leveraging prior quantitative knowledge to guide drug development decisions and regulatory science recommendations: impact of FDA pharmacometrics during 2004-2006.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Impact of pharmacometric reviews on new drug approval and labeling decisions--a survey of 31 new drug applications submitted between 2005 and 2006.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Impact of pharmacometrics on drug approval and labeling decisions: a survey of 42 new drug applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Concepts and usefulness of pharmacokinetic-pharmacodynamic modelling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Pharmacokinetic/pharmacodynamic modeling in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Model-based drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Learning versus confirming in clinical drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

The clinical utility index as a practical multiattribute approach to drug development decisions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Risk factors and clinical impact of postoperative symptomatic venous thromboembolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Venous thromboembolism in elective operations: balancing the choices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Prevention of postoperative venous thromboembolism in Japanese patients undergoing total hip or knee arthroplasty: two randomized, double-blind, placebo-controlled studies with three dosage regimens of enoxaparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Prospective evaluation of a D-optimal designed population pharmacokinetic study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Development and evaluation of a population pharmacokinetic-pharmacodynamic model of darbepoetin alfa in patients with nonmyeloid malignancies undergoing multicycle chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

Apixaban, an oral direct factor Xa inhibitor, inhibits human clot-bound factor Xa activity in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

7 January 2021

A multi-dimensional model of clinical utility

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

7 January 2021

Clinical and economic consequences of bleeding following major orthopedic surgery

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

7 January 2021

Human gene mapping 3. Baltimore Conference (1975). Third International Workshop on Human Gene Mapping. Report of the committee on the genetic constitution of autosomes other than chromosomes 1, 2, and 6

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.106

7 January 2021

Identifiers

DOI

10.1038/CLPT.2010.106

1 reference

11 November 2017

1 reference