(Q42962467)

11 November 2017

The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function (English)

1 reference

frontotemporal lobar degeneration

11 November 2017

0 references

1 reference

Owen A Brady

1

1 reference

11 November 2017

Yanqiu Zheng

2

1 reference

11 November 2017

Kira Murphy

3

1 reference

11 November 2017

Marshall Huang

4

1 reference

11 November 2017

Fenghua Hu

5

1 reference

11 November 2017

6 November 2012

1 reference

11 November 2017

Human Molecular Genetics

1 reference

11 November 2017

22

1 reference

11 November 2017

4

1 reference

11 November 2017

685-695

1 reference

TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

TMEM106B a novel risk factor for frontotemporal lobar degeneration

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Frontotemporal lobar degeneration genome wide association study replication confirms a risk locus shared with amyotrophic lateral sclerosis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

The granulin gene family: from cancer to dementia

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

The regulation and function of Class III PI3Ks: novel roles for Vps34.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Use of polyethyleneimine polymer in cell culture as attachment factor and lipofection enhancer

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

The prevalence of frontotemporal dementia

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Use of fluorescein isothiocyanate-dextran to measure proton pumping in lysosomes and related organelles

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

The functional analysis of the CHMP2B missense mutation associated with neurodegenerative diseases in the endo-lysosomal pathway.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

Clinical, genetic, and pathologic characteristics of patients with frontotemporal dementia and progranulin mutations.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3554197

16 August 2018

Frontotemporal dementia

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDS475

TMEM106B is a susceptibility locus for Ftld

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23136129

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDS475

1 reference

11 November 2017

1 reference

11 November 2017

PubMed publication ID

23136129

1 reference