(Q42964673)

11 November 2017

A novel strategy for designing the selective PPAR agonist by the "sum of activity" model (English)

1 reference

11 November 2017

Hung-Jin Huang

1

1 reference

11 November 2017

Kuei-Jen Lee

2

1 reference

11 November 2017

Hsin Wei Yu

3

1 reference

11 November 2017

Hsin-Yi Chen

4

1 reference

11 November 2017

Fuu-Jen Tsai

5

1 reference

11 November 2017

Calvin Yu-Chian Chen

6

1 reference

11 November 2017

1 October 2010

1 reference

Journal of Biomolecular Structure and Dynamics

11 November 2017

1 reference

11 November 2017

28

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11 November 2017

2

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11 November 2017

187-200

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The medical risks of obesity

11 November 2017

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Significance of peroxisome proliferator-activated receptors in the cardiovascular system in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Puerariae radix isoflavones and their metabolites inhibit growth and induce apoptosis in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Activation of nuclear hormone receptor peroxisome proliferator-activated receptor-delta accelerates intestinal adenoma growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Cell cross-talk mediates PPAR null hepatocyte proliferation after peroxisome proliferator exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Cyclooxygenase inhibitors induce colon cancer cell apoptosis Via PPARdelta --> 14-3-3epsilon pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

PPARdelta is pro-tumorigenic in a mouse model of COX-2-induced mammary cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Localization of PPARdelta in murine central nervous system: expression in oligodendrocytes and neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

PPAR-β/δ agonists for Type 2 diabetes and dyslipidemia: an adopted orphan still looking for a home

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

7-Chloroarctinone-b as a new selective PPARgamma antagonist potently blocks adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Berberine inhibits 3T3-L1 adipocyte differentiation through the PPARgamma pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

PPARgamma in the control of brown adipocyte differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

PPARalpha and dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

PPARalpha, but not PPARgamma, activators decrease macrophage-laden atherosclerotic lesions in a nondiabetic mouse model of mixed dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Fluid retention mediated by renal PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

PPAR modulators and PPAR pan agonists for metabolic diseases: the next generation of drugs targeting peroxisome proliferator-activated receptors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Selective PPAR modulators, dual and pan PPAR agonists: multimodal drugs for the treatment of type 2 diabetes and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

The Effect of PPARalpha, PPARdelta, PPARgamma, and PPARpan Agonists on Body Weight, Body Mass, and Serum Lipid Profiles in Diet-Induced Obese AKR/J Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

An insight to the dynamics of conserved water molecular triad in IMPDH II (human): recognition of cofactor and substrate to catalytic Arg 322.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Molecular dynamics simulations to investigate the structural stability and aggregation behavior of the GGVVIA oligomers derived from amyloid beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Molecular dynamics simulations to gain insights into the stability and morphologies of K3 oligomers from beta2-microglobulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Reconstructing potentials of mean force from short steered molecular dynamics simulations of Vpu from HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Disruption mechanism in the helix of SPF peptide by interchanging E5 and K10 residues: inference from molecular dynamics study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Studies on the structural stability of rabbit prion probed by molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Molecular dynamics simulations to investigate the aggregation behaviors of the Abeta(17-42) oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Investigation of the effect of glycosylation on human prion protein by molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Construction and assessment of reaction models of class I EPSP synthase: molecular docking and density functional theoretical calculations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

A docking study using atomistic conformers generated via elastic network model for cyclosporin A/cyclophilin A complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Homology modeling of GLUT4, an insulin regulated facilitated glucose transporter and docking studies with ATP and its inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Homology modeling of wild-type, D516V, and H526L Mycobacterium tuberculosis RNA polymerase and their molecular docking study with inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Molecular dynamics, flexible docking, virtual screening, ADMET predictions, and molecular interaction field studies to design novel potential MAO-B inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Ligand-based dual target drug design for H1N1: swine flu--a preliminary first study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

Indanylacetic acid derivatives carrying 4-thiazolyl-phenoxy tail groups, a new class of potent PPAR alpha/gamma/delta pan agonists: synthesis, structure-activity relationship, and in vivo efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

FUGUE: sequence-structure homology recognition using environment-specific substitution tables and structure-dependent gap penalties

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

HINT: a new method of empirical hydrophobic field calculation for CoMFA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

'Sum of activities' as dependent parameter: a new CoMFA-based approach for the design of pan PPAR agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2010.10507352

10.1080/07391102.2010.10507352

21 January 2018

Identifiers

DOI

1 reference

11 November 2017

1 reference