(Q42966206)

11 November 2017

Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats (English)

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11 November 2017

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Xiaodong Li

1

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11 November 2017

Kelly S Warmington

2

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11 November 2017

Qing-Tian Niu

3

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11 November 2017

Franklin J Asuncion

4

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11 November 2017

Mauricio Barrero

5

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11 November 2017

Mario Grisanti

6

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11 November 2017

Denise Dwyer

7

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11 November 2017

Brian Stouch

8

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11 November 2017

Theingi M Thway

9

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11 November 2017

Marina Stolina

10

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11 November 2017

Michael S Ominsky

11

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11 November 2017

Paul J Kostenuik

12

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11 November 2017

William S Simonet

13

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11 November 2017

Chris Paszty

14

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11 November 2017

Hua Zhu Ke

15

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11 November 2017

16 July 2010

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Journal of Bone and Mineral Research

11 November 2017

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11 November 2017

25

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11 November 2017

12

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11 November 2017

2647-2656

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11 November 2017

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Epidemiology of osteoporosis and fracture in men.

21 January 2018

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Male osteoporosis: deadly, but ignored

21 January 2018

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Osteoporosis in men: pathophysiology and treatment.

21 January 2018

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Bone structure and metabolism in a rodent model of male senile osteoporosis.

21 January 2018

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Predictors of bone mineral density in aging healthy men varies by skeletal site

21 January 2018

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Male rodent model of age-related bone loss in men.

21 January 2018

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21 January 2018

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Age-dependent Wnt gene expression in bone and during the course of osteoblast differentiation

21 January 2018

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Lasofoxifene (CP-336,156) protects against the age-related changes in bone mass, bone strength, and total serum cholesterol in intact aged male rats

21 January 2018

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Effects of cerivastatin and parathyroid hormone on the lumbar vertebra of aging male Sprague-Dawley rats

21 January 2018

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Site-specific effects of cerivastatin on bone in male Sprague-Dawley rats

21 January 2018

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Parathyroid hormone induces formation of new cancellous bone with substantial mechanical strength at a site where it had disappeared in old rats

21 January 2018

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Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein

21 January 2018

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Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)

21 January 2018

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Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

21 January 2018

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Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

21 January 2018

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Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

21 January 2018

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SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

21 January 2018

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Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

21 January 2018

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Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity

21 January 2018

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LRP5 mutations linked to high bone mass diseases cause reduced LRP5 binding and inhibition by SOST.

21 January 2018

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Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis

21 January 2018

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A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis

21 January 2018

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RANKL inhibition with osteoprotegerin increases bone strength by improving cortical and trabecular bone architecture in ovariectomized rats

21 January 2018

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

21 January 2018

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Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats

21 January 2018

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Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

21 January 2018

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Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum

21 January 2018

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Increased RANK ligand in bone marrow of orchiectomized rats and prevention of their bone loss by the RANK ligand inhibitor osteoprotegerin.

21 January 2018

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Intermittently administered parathyroid hormone 1-34 reverses bone loss and structural impairment in orchiectomized adult rats.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JBMR.182

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11 November 2017

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