(Q42971801)

English

Cytotoxic T lymphocyte antigen 4 is induced in the thymus upon in vivo activation and its blockade prevents anti-CD3-mediated depletion of thymocytes

scientific article published on October 1998

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scholarly article

1 reference

Europe PubMed Central

12 November 2017

Cytotoxic T lymphocyte antigen 4 is induced in the thymus upon in vivo activation and its blockade prevents anti-CD3-mediated depletion of thymocytes (English)

1 reference

Europe PubMed Central

12 November 2017

0 references

author name string

C M Cilio

1

1 reference

Europe PubMed Central

12 November 2017

M R Daws

2

1 reference

Europe PubMed Central

12 November 2017

A Malashicheva

3

1 reference

Europe PubMed Central

12 November 2017

C L Sentman

4

1 reference

Europe PubMed Central

12 November 2017

D Holmberg

5

1 reference

Europe PubMed Central

12 November 2017

language of work or name

0 references

publication date

1 October 1998

1 reference

Europe PubMed Central

12 November 2017

Journal of Experimental Medicine

1 reference

Europe PubMed Central

12 November 2017

188

1 reference

Europe PubMed Central

12 November 2017

7

1 reference

Europe PubMed Central

12 November 2017

1239-1246

1 reference

Europe PubMed Central

12 November 2017

The emerging role of CTLA-4 as an immune attenuator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Thymocyte development is normal in CTLA-4-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Co-stimulation in T cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

A family of proteins that inhibit signalling through tyrosine kinase receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Negative selection in the thymus includes semimature T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

CTLA-4, a negative regulator of T-lymphocyte activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

CD28-B7 interactions function to co-stimulate clonal deletion of double-positive thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Analysis of the site of interaction of CD28 with its counter-receptors CD80 and CD86 and correlation with function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Medullary thymic epithelium expresses a ligand for CTLA4 in situ and in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

CTLA-4 can function as a negative regulator of T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Development and selection of T cells: facts and puzzles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Positive selection of thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

A new member of the immunoglobulin superfamily--CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

CTLA-4 is a second receptor for the B cell activation antigen B7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Thymic selection: a matter of life and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Identification and distribution of the costimulatory receptor CD28 in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

26 May 2018

CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

16 August 2018

The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

16 August 2018

https://api.crossref.org/works/10.1084%2FJEM.188.7.1239

21 January 2018

Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice

2 references

https://api.crossref.org/works/10.1084%2FJEM.188.7.1239

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Is CTLA-4 a negative regulator for T-cell activation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Genetic markers in diagnosis and prediction of relapse in Graves' disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Regulation of surface and intracellular expression of CTLA4 on mouse T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Evidence that induction of tolerance in vivo involves active signaling via a B7 ligand-dependent mechanism: CTLA4-Ig protects V beta 8+ T cells from tolerance induction by the superantigen staphylococcal enterotoxin B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212496

3 November 2018

Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.7.1239

21 January 2018

Human Influence on the Atmospheric Vertical Temperature Structure: Detection and Observations

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.7.1239

21 January 2018

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1 reference

https://api.crossref.org/works/10.1084%2FJEM.188.7.1239

21 January 2018

Thymus cell migration: analysis of thymus emigrants with markers that distinguish medullary thymocytes from peripheral T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9763603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/9763603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1084/JEM.188.7.1239

1 reference

Europe PubMed Central

12 November 2017

1 reference

Europe PubMed Central

12 November 2017

1 reference

Europe PubMed Central

12 November 2017

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