(Q41332143)

29 September 2017

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title

CTLA-4, a negative regulator of T-lymphocyte activation (English)

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29 September 2017

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P Waterhouse

1

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29 September 2017

L E Marengère

series ordinal

2

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29 September 2017

H W Mittrücker

series ordinal

3

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29 September 2017

T W Mak

series ordinal

4

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29 September 2017

publication date

1 October 1996

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29 September 2017

published in

Immunological Reviews

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29 September 2017

volume

153

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29 September 2017

page(s)

183-207

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Signal transduction through the T-cell antigen receptor

29 September 2017

cites work

1 reference

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B70 antigen is a second ligand for CTLA-4 and CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Functional expression of B7/BB1 on activated T lymphocytes

21 January 2018

1 reference

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The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Inositol trisphosphate and calcium signalling

21 January 2018

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Protein tyrosine kinases in the initiation of antigen receptor signaling

21 January 2018

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A new member of the immunoglobulin superfamily--CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Extracellular signals and reversible protein phosphorylation: what to Mek of it all.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

21 January 2018

1 reference

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Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Multiple kinases mediate T-cell-receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Protein-tyrosine phosphatases: the other side of the coin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Differential effects of expression of the CD45 tyrosine protein phosphatase on the tyrosine phosphorylation of the lck, fyn, and c-src tyrosine protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

The B7 and CD28 receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Control of transcription factors by signal transduction pathways: the beginning of the end

21 January 2018

1 reference

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Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Binding stoichiometry of the cytotoxic T lymphocyte-associated molecule-4 (CTLA-4). A disulfide-linked homodimer binds two CD86 molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

T cell antigen receptor signaling: three families of tyrosine kinases and a phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Ligation of the T-cell Antigen Receptor (TCR) Induces Association of hSos1, ZAP-70, Phospolipase C- 1, and Other Phosphoproteins with Grb2 and the -Chain of the TCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Nucleotide sequence of the ACI rat CTLA-4 molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Lymphocyte ontogeny and activation in gene targeted mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Guanine nucleotide exchange factors: activators of the Ras superfamily of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

The mechanism of action of cyclosporin A and FK506

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Of ITAMs and ITIMs: turning on and off the B cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

CTLA-4 can function as a negative regulator of T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

CD8+ T-cell clones deficient in the expression of the CD45 protein tyrosine phosphatase have impaired responses to T-cell receptor stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Signal transduction by lymphocyte antigen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

A functional T-cell receptor signaling pathway is required for p95vav activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Structural basis for the binding of proline-rich peptides to SH3 domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Modular binding domains in signal transduction proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Distinct isoforms of the CD45 protein-tyrosine phosphatase differentially regulate interleukin 2 secretion and activation signal pathways involving Vav in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

A comparison of the interaction of Shc and the tyrosine kinase ZAP-70 with the T cell antigen receptor zeta chain tyrosine-based activation motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Evidence that the leukocyte-common antigen is required for antigen-induced T lymphocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

Constitutive Tyrosine Phosphorylation of the T-Cell Receptor (TCR) ζ Subunit: Regulation of TCR-Associated Protein Tyrosine Kinase Activity by TCR ζ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1996.TB00925.X

10.1111/J.1600-065X.1996.TB00925.X

21 January 2018

Identifiers

DOI

1 reference

29 September 2017

1 reference