(Q42988355)

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Coimmunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII.

scientific article published on 6 March 2009

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Europe PubMed Central

PubMed publication ID

12 November 2017

Coimmunization with an optimized IL15 plasmid adjuvant enhances humoral immunity via stimulating B cells induced by genetically engineered DNA vaccines expressing consensus JEV and WNV E DIII. (English)

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12 November 2017

West Nile virus

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David B. Weiner

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David B Weiner

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Mathura P Ramanathan

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12 November 2017

Michele A Kutzler

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12 November 2017

Yuan-Chia Kuo

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12 November 2017

Jian Yan

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Harrison Liu

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Vidhi Shah

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Amrit Bawa

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Bernard Selling

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Niranjan Y Sardesai

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J Joseph Kim

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6 March 2009

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12 November 2017

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4370-4380

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12 November 2017

Exotic and emerging viral encephalitides

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DC-SIGN enhances infection of cells with glycosylated West Nile virus in vitro and virus replication in human dendritic cells induces production of IFN-alpha and TNF-alpha

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Immunization with West Nile virus envelope domain III protects mice against lethal infection with homologous and heterologous virus

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Immunization of flavivirus West Nile recombinant envelope domain III protein induced specific immune response and protection against West Nile virus infection.

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Induction of protective antibodies against dengue virus by tetravalent DNA immunization of mice with domain III of the envelope protein

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Molecular characterization of a neutralizing domain of the Japanese encephalitis virus structural glycoprotein

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Immunogenicity and protective efficacy of the E. coli-expressed domain III of Japanese encephalitis virus envelope protein in mice

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Diversity considerations in HIV-1 vaccine selection

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Enhanced cellular immune responses elicited by an engineered HIV-1 subtype B consensus-based envelope DNA vaccine

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Electroporation of synthetic DNA antigens offers protection in nonhuman primates challenged with highly pathogenic avian influenza virus

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Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus

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Immunogenicity testing of a novel engineered HIV-1 envelope gp140 DNA vaccine construct

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Parameters for DNA vaccination using adaptive constant-current electroporation in mouse and pig models.

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A novel autoregulatory mechanism for transcriptional activation of the IL-15 gene by a nonsecretable isoform of IL-15 generated by alternative splicing.

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A novel role of IL-15 in early activation of memory CD8+ CTL after reinfection.

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Regression of subcutaneous B16 melanoma tumors after intratumoral delivery of an IL-15-expressing plasmid followed by in vivo electroporation

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Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help.

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Cytokine control of memory T-cell development and survival

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10.1016/J.VACCINE.2009.01.137

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 November 2017

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