(Q42989591)

12 November 2017

A rate equation approach to elucidate the kinetics and robustness of the TGF-beta pathway (English)

1 reference

12 November 2017

Pontus Melke

1

1 reference

12 November 2017

Henrik Jönsson

2

1 reference

12 November 2017

Evangelia Pardali

3

1 reference

12 November 2017

Peter ten Dijke

4

1 reference

12 November 2017

Carsten Peterson

5

1 reference

12 November 2017

language of work or name

English

0 references

publication date

29 September 2006

1 reference

12 November 2017

1 reference

12 November 2017

91

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12 November 2017

12

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12 November 2017

4368-4380

1 reference

Optimization by Simulated Annealing

12 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Signal processing in the TGF-beta superfamily ligand-receptor network

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

New insights into TGF-beta-Smad signalling

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Computational modeling of the dynamics of the MAP kinase cascade activated by surface and internalized EGF receptors

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Role of transforming growth factor beta in human disease

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Non-linear optimization of biochemical pathways: applications to metabolic engineering and parameter estimation

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Induction of Smad6 mRNA by bone morphogenetic proteins

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1779910

10.1529/BIOPHYSJ.105.080408

16 August 2018

Identifiers

DOI

1 reference

12 November 2017

1 reference

12 November 2017

PubMed publication ID

17012329

1 reference