(Q52065307)

21 April 2018

title

A computational study of feedback effects on signal dynamics in a mitogen-activated protein kinase (MAPK) pathway model. (English)

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21 April 2018

main subject

computational biology

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based on heuristic

inferred from title

author

Douglas A. Lauffenburger

series ordinal

2

object named as

Lauffenburger DA

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21 April 2018

author name string

Asthagiri AR

series ordinal

1

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21 April 2018

publication date

1 March 2001

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21 April 2018

published in

Biotechnology Progress

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21 April 2018

volume

17

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21 April 2018

page(s)

227-239

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21 April 2018

issue

2

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21 April 2018

Robustness in bacterial chemotaxis

cites work

1 reference

Raf-1 is a potential substrate for mitogen-activated protein kinase in vivo

21 January 2018

1 reference

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

21 January 2018

1 reference

Quantitative relationship among integrin-ligand binding, adhesion, and signaling via focal adhesion kinase and extracellular signal-regulated kinase 2.

21 January 2018

1 reference

Bioengineering models of cell signaling

21 January 2018

1 reference

Robustness in simple biochemical networks

21 January 2018

1 reference

Growth factor-stimulated MAP kinase induces rapid retrophosphorylation and inhibition of MAP kinase kinase (MEK1)

21 January 2018

1 reference

SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways

21 January 2018

1 reference

Identification of the mitogen-activated protein kinase phosphorylation sites on human Sos1 that regulate interaction with Grb2

21 January 2018

1 reference

Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

21 January 2018

1 reference

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

21 January 2018

1 reference

Activation of the mitogen-activated protein kinase pathway induces transcription of the PAC-1 phosphatase gene

21 January 2018

1 reference

Signaling through focal adhesion kinase

21 January 2018

1 reference

Physical modulation of intracellular signaling processes by locational regulation

21 January 2018

1 reference

Ultrasensitivity in the mitogen-activated protein kinase cascade

21 January 2018

1 reference

Ras effectors and their role in mitogenesis and oncogenesis

21 January 2018

1 reference

Functional genomic technologies: creating new paradigms for fundamental and applied biology

21 January 2018

1 reference

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

21 January 2018

1 reference

Amplification and adaptation in regulatory and sensory systems.

21 January 2018

1 reference

Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation

21 January 2018

1 reference

Cell signaling pathways as control modules: complexity for simplicity?

21 January 2018

1 reference

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

21 January 2018

1 reference

Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

21 January 2018

1 reference

Targeting signal transduction for disease therapy

21 January 2018

1 reference

Mitogen-activated protein kinase cascade in breast cancer

21 January 2018

1 reference

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

Physical association with ras enhances activation of membrane-bound raf (RafCAAX).

21 January 2018

1 reference

Alpha5beta1 integrin controls cyclin D1 expression by sustaining mitogen-activated protein kinase activity in growth factor-treated cells

21 January 2018

1 reference

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

21 January 2018

1 reference

Anchorage-dependent transcription of the cyclin A gene

21 January 2018

1 reference

Activation of Raf as a result of recruitment to the plasma membrane

21 January 2018

1 reference

The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic.

21 January 2018

1 reference

Robust perfect adaptation in bacterial chemotaxis through integral feedback control

21 January 2018

1 reference

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor

21 January 2018

1 reference

EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

21 January 2018

1 reference

Negative Modulation of Membrane Localization of the Raf-1 Protein Kinase by Hyperphosphorylation

21 January 2018

1 reference

The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade

21 January 2018

1 reference

Signal transduction through MAP kinase cascades

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1021/BP010009K

1 reference

21 April 2018

PubMed ID

11312698

1 reference

21 April 2018