(Q42996554)

12 November 2017

title

Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded (English)

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12 November 2017

6

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12 November 2017

Natalia Lyashenko

1

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12 November 2017

Martina Weissenböck

2

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12 November 2017

Amnon Sharir

3

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12 November 2017

Reinhold G Erben

4

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12 November 2017

Yasuhiro Minami

5

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12 November 2017

publication date

1 August 2010

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12 November 2017

published in

Developmental Dynamics

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12 November 2017

volume

239

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12 November 2017

issue

8

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12 November 2017

page(s)

2266-2277

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Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2.

12 November 2017

cites work

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Expression of the Ror1 and Ror2 receptor tyrosine kinase genes during mouse development

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HIF1alpha regulation of Sox9 is necessary to maintain differentiation of hypoxic prechondrogenic cells during early skeletogenesis.

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Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones

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7 January 2021

Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia.

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7 January 2021

Pallister-Hall syndrome phenotype in mice mutant for Gli3

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Wnt signaling mediates regional specification in the vertebrate face

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7 January 2021

Ror1, a cell surface receptor tyrosine kinase is expressed in chronic lymphocytic leukemia and may serve as a putative target for therapy

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7 January 2021

Ror2, encoding a receptor-like tyrosine kinase, is required for cartilage and growth plate development

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7 January 2021

Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling

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7 January 2021

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

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7 January 2021

Ror receptor tyrosine kinases: orphans no more

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7 January 2021

Brachydactyly type B1: report of a family with de novo ROR2 mutation

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7 January 2021

Wnt5a regulates directional cell migration and cell proliferation via Ror2-mediated noncanonical pathway in mammalian palate development

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7 January 2021

Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival

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7 January 2021

BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye.

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7 January 2021

Ror2 expression in squamous cell carcinoma and epithelial dysplasia of the oral cavity.

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7 January 2021

Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2

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7 January 2021

Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase

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7 January 2021

Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

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7 January 2021

Organisation of bone morphogenetic proteins in renal development

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7 January 2021

Expression of the receptor tyrosine kinase genes, Ror1 and Ror2, during mouse development.

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7 January 2021

Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S.

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7 January 2021

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

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7 January 2021

Postnatally elevated levels of insulin-like growth factor (IGF)-II fail to rescue the dwarfism of IGF-I-deficient mice except kidney weight

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7 January 2021

Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma

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7 January 2021

Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling

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7 January 2021

Insulin-like growth factor-I augments chondrocyte hypertrophy and reverses glucocorticoid-mediated growth retardation in fetal mice metatarsal cultures.

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7 January 2021

Loss of mRor1 enhances the heart and skeletal abnormalities in mRor2-deficient mice: redundant and pleiotropic functions of mRor1 and mRor2 receptor tyrosine kinases

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7 January 2021

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma

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7 January 2021

Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous system

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7 January 2021

The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway

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7 January 2021

Dominant mutations in ROR2, encoding an orphan receptor tyrosine kinase, cause brachydactyly type B

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7 January 2021

Expression and subcellular localization of Ror tyrosine kinase receptors are developmentally regulated in cultured hippocampal neurons

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7 January 2021

Wnt signaling in kidney development and disease.

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7 January 2021

Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development

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7 January 2021

The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

Effect of growth hormone and insulin-like growth factor I (IGF-I) on the expression of IGF-I messenger ribonucleic acid and peptide in rat tibial growth plate and articular chondrocytes in vivo

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7 January 2021

Sonic hedgehog mediates the polarizing activity of the ZPA

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7 January 2021

Expression and regulation of ROR-1 during early avian limb development

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7 January 2021

Identification of a Frizzled-like cysteine rich domain in the extracellular region of developmental receptor tyrosine kinases

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7 January 2021

Modulation of GDF5/BRI-b signalling through interaction with the tyrosine kinase receptor Ror2.

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7 January 2021

High cortical bone mass phenotype in betacellulin transgenic mice is EGFR dependent.

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7 January 2021

Distinct mutations in the receptor tyrosine kinase gene ROR2 cause brachydactyly type B.

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7 January 2021

Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome

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7 January 2021

Overexpression of orphan receptor tyrosine kinase Ror1 as a putative tumor-associated antigen in Iranian patients with acute lymphoblastic leukemia

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7 January 2021

Expression profile of orphan receptor tyrosine kinase (ROR1) and Wilms' tumor gene 1 (WT1) in different subsets of B-cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived IGF-I.

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7 January 2021

IGF and IGF-binding protein expression in the growth plate of normal, dexamethasone-treated and human IGF-II transgenic mice

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https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

Mouse Ror2 receptor tyrosine kinase is required for the heart development and limb formation

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndrome

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

Ror2, a developmentally regulated kinase, promotes tumor growth potential in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

Normal growth and development in the absence of hepatic insulin-like growth factor I

1 reference

https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

Expression and function of the Ror-family receptor tyrosine kinases during development: lessons from genetic analyses of nematodes, mice, and humans

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https://api.crossref.org/works/10.1002%2FDVDY.22362

7 January 2021

Identifiers

DOI

10.1002/DVDY.22362

1 reference

12 November 2017

1 reference