(Q28585489)

English

Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones

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scholarly article

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31 January 2017

Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones (English)

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31 January 2017

Transforming growth factor, beta 2

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GOA release 2020-03-11

Harold L. Moses

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object named as

Harold L. Moses

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31 January 2017

author name string

Michael O. Baffi

1

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31 January 2017

Erin Slattery

2

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31 January 2017

Philip Sohn

3

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31 January 2017

Anna Chytil

5

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31 January 2017

Rosa Serra

6

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31 January 2017

language of work or name

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publication date

1 December 2004

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31 January 2017

Developmental Biology

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31 January 2017

276

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31 January 2017

124–142

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31 January 2017

1

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31 January 2017

The perichondrium plays an important role in mediating the effects of TGF-beta1 on endochondral bone formation

1 reference

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Cloning of the human and mouse type X collagen genes and mapping of the mouse type X collagen gene to chromosome 10

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Collagen II is essential for the removal of the notochord and the formation of intervertebral discs

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Impaired intervertebral disc formation in the absence of Jun.

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Expression of a dominant-negative mutant TGF-beta type II receptor in transgenic mice reveals essential roles for TGF-beta in regulation of growth and differentiation in the exocrine pancreas

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Genetic analysis of the mammalian transforming growth factor-beta superfamily

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The development of the avian vertebral column

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Conditional inactivation of the TGF-beta type II receptor using Cre:Lox

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Bone abnormalities in latent TGF-[beta] binding protein (Ltbp)-3-null mice indicate a role for Ltbp-3 in modulating TGF-[beta] bioavailability

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Cellular interactions and signaling in cartilage development

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TGF-beta-receptor-mediated signaling

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Intracellular signalling: the mad way to do it.

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Regulation of endochondral cartilage growth in the developing avian limb: cooperative involvement of perichondrium and periosteum

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Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects

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BMP7 null mutation in mice: developmental defects in skeleton, kidney, and eye.

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Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction

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A rapid procedure for routine double staining of cartilage and bone in fetal and adult animals.

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What do BMPs do in mammals? Clues from the mouse short-ear mutation

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Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning

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TGFbeta signaling in growth control, cancer, and heritable disorders

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Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S.

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Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

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Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development.

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Perturbation of BMP signaling in somitogenesis resulted in vertebral and rib malformations in the axial skeletal formation.

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Modulation of the biologic activity of the rabbit intervertebral disc by gene therapy: an in vivo study of adenovirus-mediated transfer of the human transforming growth factor beta 1 encoding gene

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TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis

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Transforming growth factor-beta 3 is required for secondary palate fusion

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Expression patterns of cartilage collagens and Sox9 during mouse heart development

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An organ culture system for the study of the nucleus pulposus: description of the system and evaluation of the cells

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An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo.

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The development of fibrocartilage in the rat intervertebral disc

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Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification

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Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: differential expression of the amino-propeptide

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Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation

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Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

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