(Q42997512)

12 November 2017

Genome sequencing of normal cells reveals developmental lineages and mutational processes (English)

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12 November 2017

whole genome sequencing

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5

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12 November 2017

6

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9

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12 November 2017

19

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12 November 2017

Ruben van Boxtel

3

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Serena Nik-Zainal

17

object named as

Serena Nik-Zainal

1 reference

12 November 2017

23

Michael R Stratton

1 reference

12 November 2017

22

Hans Clevers

1 reference

12 November 2017

20

Marc van de Wetering

1 reference

12 November 2017

2

Meritxell Huch

1 reference

12 November 2017

1

Sam Behjati

1 reference

12 November 2017

12

Sophie Roerink

1 reference

12 November 2017

Wouter Karthaus

4

1 reference

12 November 2017

Inigo Martincorena

7

1 reference

12 November 2017

Mia Petljak

8

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12 November 2017

Gunes Gundem

10

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12 November 2017

Patrick S Tarpey

11

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12 November 2017

Joyce Blokker

13

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12 November 2017

Mark Maddison

14

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12 November 2017

Laura Mudie

15

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12 November 2017

Ben Robinson

16

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12 November 2017

Peter Campbell

18

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12 November 2017

Edwin Cuppen

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12 November 2017

language of work or name

English

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publication date

29 June 2014

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12 November 2017

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12 November 2017

513

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12 November 2017

422-425

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12 November 2017

7518

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https://scigraph.springernature.com/pub.10.1038/nature13448

12 November 2017

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cites work

Signatures of mutational processes in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Single-cell sequencing-based technologies will revolutionize whole-organism science

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Mutational heterogeneity in cancer and the search for new cancer-associated genes

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Use of somatic mutations to quantify random contributions to mouse development

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Deciphering signatures of mutational processes operative in human cancer

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Mutational processes molding the genomes of 21 breast cancers

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

The life history of 21 breast cancers

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Molecular phylogenetics: principles and practice

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Decoding cell lineage from acquired mutations using arbitrary deep sequencing

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Somatic mutations in aging, cancer and neurodegeneration

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Somatic mosaicism in healthy human tissues

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Developmental control of the early mammalian embryo: competition among heterogeneous cells that biases cell fate

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Reconstruction of cell lineage trees in mice

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Identification of stem cells in small intestine and colon by marker gene Lgr5

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

A phylogenetic approach to mapping cell fate

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Counting divisions in a human somatic cell tree: how, what and why?

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Phylogenetic fate mapping

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

The first cleavage of the mouse zygote predicts the blastocyst axis.

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Lgr5(+) gastric stem cells divide symmetrically to effect epithelial homeostasis in the pylorus

26 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Single-cell sequencing in its prime

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Chromatin organization is a major influence on regional mutation rates in human cancer cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Very long-term self-renewal of small intestine, colon, and hair follicles from cycling Lgr5+ve stem cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4227286

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

16 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25043003

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE13448

1 reference

12 November 2017

1 reference

12 November 2017

1 reference