(Q43000694)

English

Correlation between mutations in the core and NS5A genes of hepatitis C virus genotypes 1a, 1b, 3a, 3b, 6f and the response to pegylated interferon and ribavirin combination therapy.

scientific article published on 19 October 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955493%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Correlation between mutations in the core and NS5A genes of hepatitis C virus genotypes 1a, 1b, 3a, 3b, 6f and the response to pegylated interferon and ribavirin combination therapy (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955493%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

based on heuristic

inferred from title

Hepatitis C virus

1 reference

based on heuristic

inferred from title

pegylated interferon

1 reference

based on heuristic

inferred from title

Kattareeya Kumthip

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955493%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

author name string

C Pantip

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20955493%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

P Chusri

3

1 reference

Europe PubMed Central

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15 February 2020

S Thongsawat

4

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15 February 2020

A O'Brien

5

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15 February 2020

K E Nelson

6

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15 February 2020

N Maneekarn

7

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15 February 2020

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publication date

19 October 2010

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15 February 2020

Journal of Viral Hepatitis

1 reference

Europe PubMed Central

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15 February 2020

18

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15 February 2020

4

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15 February 2020

e117-25

1 reference

Europe PubMed Central

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15 February 2020

Treatment of hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Mechanisms of antiviral treatment efficacy and failure in chronic hepatitis C.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Hepatitis C virus core protein blocks interferon signaling by interaction with the STAT1 SH2 domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Comparison of full-length sequences of interferon-sensitive and resistant hepatitis C virus 1b. Sensitivity to interferon is conferred by amino acid substitutions in the NS5A region

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Pretreatment virus load and multiple amino acid substitutions in the interferon sensitivity-determining region predict the outcome of interferon treatment in patients with chronic genotype 1b hepatitis C virus infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Number and position of mutations in the interferon (IFN) sensitivity-determining region of the gene for nonstructural protein 5A correlate with IFN efficacy in hepatitis C virus genotype 1b infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

A mutation in the interferon sensitivity-determining region is associated with responsiveness to interferon-ribavirin combination therapy in chronic hepatitis patients infected with a Japan-specific subtype of hepatitis C virus genotype 1B.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Prospective characterization of full-length hepatitis C virus NS5A quasispecies during induction and combination antiviral therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

[Mutation analysis of ISDR and V3 domains of hepatitis C virus NS5A region before interferon therapy with or without ribavirin]

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Prediction of efficient virological response to pegylated interferon/ribavirin combination therapy by NS5A sequences of hepatitis C virus and anti-NS5A antibodies in pre-treatment sera

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Sequence variation in hepatitis C virus nonstructural protein 5A predicts clinical outcome of pegylated interferon/ribavirin combination therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Association of amino acid substitution pattern in core protein of hepatitis C virus genotype 1b high viral load and non-virological response to interferon-ribavirin combination therapy.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Predictive factors of virological non-response to interferon-ribavirin combination therapy for patients infected with hepatitis C virus of genotype 1b and high viral load.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Hepatitis C virus-related resistance mechanisms to interferon alpha-based antiviral therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Treatment failure in hepatitis C: mechanisms of non-response.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Peginterferon alfa-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Mutations in the nonstructural 5A gene of European hepatitis C virus isolates and response to interferon alfa

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Peginterferon and ribavirin treatment in African American and Caucasian American patients with hepatitis C genotype 1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Peginterferon Pharmacokinetics in African American and Caucasian American Patients With Hepatitis C Virus Genotype 1 Infection

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Sustained virological response in hepatitis C virus type 1b infected patients is predicted by the number of mutations within the NS5A-ISDR: a meta-analysis focused on geographical differences

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Variability of the nonstructural 5A protein of hepatitis C virus type 3a isolates and relation to interferon sensitivity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Predictive values of amino acid sequences of the core and NS5A regions in antiviral therapy for hepatitis C: a Japanese multi-center study

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

The NS5A protein of hepatitis C virus is a zinc metalloprotein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Function follows form: the structure of the N-terminal domain of HCV NS5A.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

Sequence analysis of the NS5A protein of European hepatitis C virus 1b isolates and relation to interferon sensitivity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2893.2010.01379.X

21 January 2018

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