(Q43050264)

English

Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole

scientific article published on 30 May 2010

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Fasciola hepatica

object named as

Fasciola hepatica

1 reference

based on heuristic

inferred from title

author name string

Catherine Devine

1

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Gerard P Brennan

2

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Carlos E Lanusse

3

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Luis I Alvarez

4

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Alan Trudgett

5

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Elizabeth Hoey

6

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Ian Fairweather

7

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

30 May 2010

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Parasitology Research

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

107

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

337-353

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

https://scigraph.springernature.com/pub.10.1007/s00436-010-1866-2

0 references

Cimetidine increases serum mebendazole concentrations. Implications for treatment of hepatic hydatid cysts

1 reference

https://api.crossref.org/works/10.1007%2FS00436-010-1866-2

21 January 2018

Triclabendazole-resistant Fasciola hepatica: beta-tubulin and response to in vitro treatment with triclabendazole.

1 reference

https://api.crossref.org/works/10.1007%2FS00436-010-1866-2

21 January 2018

Methimazole-mediated enhancement of albendazole oral bioavailability and anthelmintic effects against parenteral stages of Trichinella spiralis in mice: the influence of the dose-regime

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methimazole increases the plasma concentrations of the albendazole metabolites of netobimin in sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fasciola hepatica: morphological effects of a combination of triclabendazole and clorsulon against mature fluke

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transmission electron microscope study on the route of entry of triclabendazole into the liver fluke, Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 monooxygenase activity in Haemonchus contortus (Nematoda)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of the efficacy of compound alpha and triclabendazole against two isolates of Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methimazole-mediated modulation of netobimin biotransformation in sheep: a pharmacokinetic assessment

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fenbendazole pharmacokinetics, metabolism, and potentiation in horses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered drug influx/efflux and enhanced metabolic activity in triclabendazole-resistant liver flukes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo metabolism of aminopyrine by the larvae of the helminth Heligmosomoides polygyrus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro antimalarial interactions between mefloquine and cytochrome P450 inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The comparative metabolism of triclabendazole sulphoxide by triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding triclabendazole resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the metabolic inhibitor, methimazole on the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics and metabolism of benzimidazole anthelmintics in ruminants

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fasciola hepatica: ultrastructural effects of a combination of triclabendazole and clorsulon against mature fluke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fasciola hepatica: histological changes in the reproductive structures of triclabendazole (TCBZ)-sensitive and TCBZ-resistant flukes after treatment in vivo with TCBZ and the related benzimidazole derivative, Compound Alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes to oxfendazole chiral kinetics and anthelmintic efficacy induced by piperonyl butoxide in horses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tegumental surface changes in juvenile Fasciola hepatica in response to treatment in vivo with triclabendazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LC-MS-MS identification of albendazole and flubendazole metabolites formed ex vivo by Haemonchus contortus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The kinetics of triclabendazole disposition in sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple oral dosing of ketoconazole increases dog exposure to ivermectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidase activities in macrocyclic-resistant and -susceptible Haemonchus contortus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the plasma concentration of albendazole sulphoxide in sheep following coadministration of parenteral netobimin and liver oxidase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of the main metabolism pathways for the flukicidal compound triclabendazole in sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between Fenbendazole and Piperonyl Butoxide: Pharmacokinetic and Pharmacodynamic Implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface changes in adult Fasciola hepatica following treatment in vivo with the experimental fasciolicide, compound alpha.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytochrome P450-mediated metabolism enhances ex vivo susceptibility of Fasciola hepatica to triclabendazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolite concentrations in plasma following treatment of cattle with five anthelmintics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytochromes P450 by antifungal imidazole derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence on the antithyroid compound methimazole on the plasma disposition of fenbendazole and oxfendazole in sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Albendazole enantiomeric metabolism and binding to cytosolic proteins in the liver fluke Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma achiral and chiral pharmacokinetic behaviour of intravenous oxfendazole co-administered with piperonyl butoxide in sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative activity of triclabendazole metabolites against the liver fluke, Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of methimazole on the kinetics of netobimin metabolites in cattle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro metabolism of moxidectin in Haemonchus contortus adult stages

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome P450 isoform inhibitors as a tool for the investigation of metabolic reactions catalyzed by human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adult triclabendazole-resistant Fasciola hepatica: surface and subsurface tegumental responses to in vitro treatment with the sulphoxide metabolite of the experimental fasciolicide compound alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triclabendazole biotransformation and comparative diffusion of the parent drug and its oxidized metabolites into Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of hydatid disease with high oral doses of mebendazole. Long-term follow-up of plasma mebendazole levels and drug interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal elimination of albendazole sulfoxide: pharmacokinetic effects of inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Response of two isolates of Fasciola hepatica to treatment with triclabendazole in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the presence of active cytochrome P450 systems in Schistosoma mansoni and Schistosoma haematobium adult worms

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative metabolism of albendazole and albendazole sulphoxide by different helminth parasites

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between ketoconazole and praziquantel in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of cimetidine ketoconazole and miconazole on the metabolism of praziquantel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I biotransformation of albendazole in lancet fluke (Dicrocoelium dendriticum).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A scanning electron microscope study on the route of entry of triclabendazole into the liver fluke, Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology and efficacy of liposome-entrapped albendazole in experimental secondary alveolar echinococcosis and effect of co-administration with cimetidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergism of rotenone by piperonyl butoxide in Haemonchus contortus and Trichostrongylus colubriformis in vitro: potential for drug-synergism through inhibition of nematode oxidative detoxification pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug transport mechanisms in helminth parasites: passive diffusion of benzimidazole anthelmintics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of triclabendazole sulphoxide-induced tegumental disruption by methimazole in a triclabendazole-resistant isolate of Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of artemether and OZ78 against triclabendazole-resistant Fasciola hepatica

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of clotrimazole on microsomal metabolism and pharmacokinetics of albendazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketoconazole increases the plasma levels of ivermectin in sheep.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Divergent structures of Caenorhabditis elegans cytochrome P450 genes suggest the frequent loss and gain of introns during the evolution of nematodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxide-supported in-vitro cytochrome P450 activities in Haemonchus contortus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance-induced changes in triclabendazole transport in Fasciola hepatica: ivermectin reversal effect.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/20512589

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00436-010-1866-2

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 November 2017

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