(Q43059195)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20485337%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Covariate analysis of QTc and T-wave morphology: new possibilities in the evaluation of drugs that affect cardiac repolarization (English)

1 reference

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2 February 2020

1 reference

1

1 reference

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2 February 2020

Johannes J. Struijk

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20485337%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Jorgen K. Kanters

4

1 reference

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2 February 2020

author name string

J Matz

3

1 reference

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2 February 2020

M P Andersen

5

1 reference

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2 February 2020

J Nielsen

6

1 reference

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2 February 2020

E Toft

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20485337%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

language of work or name

English

0 references

publication date

19 May 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20485337%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacology & Therapeutics

2 February 2020

published in

1 reference

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2 February 2020

volume

88

1 reference

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2 February 2020

issue

1

1 reference

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2 February 2020

page(s)

88-94

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Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling

2 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Drug-induced torsades de pointes and implications for drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Drug-induced QT prolongation and proarrhythmia: an inevitable link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

The long QT syndrome. Prospective longitudinal study of 328 families

21 January 2018

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https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Drug-induced prolongation of the QT interval

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Drug block of I(kr): model systems and relevance to human arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Repolarization morphology in adult LQT2 carriers with borderline prolonged QTc interval.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Baseline values and sotalol-induced changes of ventricular repolarization duration, heterogeneity, and instability in patients with a history of drug-induced torsades de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Impaired T-amplitude adaptation to heart rate characterizes I(Kr) inhibition in the congenital and acquired forms of the long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

T wave morphology analysis distinguishes between KvLQT1 and HERG mutations in long QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Classification of the long-QT syndrome based on discriminant analysis of T-wave morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

The morphology of the QT interval predicts torsade de pointes during acquired bradyarrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

New descriptors of T-wave morphology are independent of heart rate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Identifying drug-induced repolarization abnormalities from distinct ECG patterns in congenital long QT syndrome: a study of sotalol effects on T-wave morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Quantitative analysis of T-wave morphology increases confidence in drug-induced cardiac repolarization abnormalities: evidence from the investigational IKr inhibitor Lu 35-138.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Sertindole causes distinct electrocardiographic T-wave morphology changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Moxifloxacin-induced QT prolongation and torsades: an uncommon effect of a common drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Torsade de pointes associated with moxifloxacin: a rare but potentially fatal adverse event

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Efficacy and safety of d,l-sotalol in patients with ventricular tachycardia and in survivors of cardiac arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Proarrhythmia with class III antiarrhythmic drugs: types, risks, and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Refining detection of drug-induced proarrhythmia: QT interval and TRIaD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Review of the predictive value of the Langendorff heart model (Screenit system) in assessing the proarrhythmic potential of drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Blinded test in isolated female rabbit heart reliably identifies action potential duration prolongation and proarrhythmic drugs: importance of triangulation, reverse use dependence, and instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Dynamic beat-to-beat modeling of the QT-RR interval relationship: analysis of QT prolongation during alterations of autonomic state versus human ether a-go-go-related gene inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Use of preclinical assays to predict risk of drug-induced torsades de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Torsade de pointes due to quinidine: observations in 31 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Concentration-QT relationships play a key role in the evaluation of proarrhythmic risk during regulatory review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Thorough QT Studies: Questions and Quandaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Decreasing the infusion rate reduces the proarrhythmic risk of NS-7: confirming the relevance of short-term variability of repolarisation in predicting drug-induced torsades de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Comparative pharmacokinetics of ciprofloxacin, gatifloxacin, grepafloxacin, levofloxacin, trovafloxacin, and moxifloxacin after single oral administration in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

No proarrhythmic properties of the antibiotics Moxifloxacin or Azithromycin in anaesthetized dogs with chronic-AV block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

The effect of moxifloxacin on QTc and implications for the design of thorough QT studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Pharmacokinetic and pharmacodynamic profiles of d-sotalol and d,l-sotalol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Electrocardiographic identification of drug-induced QT prolongation: assessment by different recording and measurement methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

Moxifloxacin and torsade de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Heterogeneity of cellular repolarization in LQTS: the role of M cells

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Torsade de pointes: the long-short initiating sequence and other clinical features: observations in 32 patients

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Beat-to-beat variability of QT intervals is increased in patients with drug-induced long-QT syndrome: a case control pilot study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Proarrhythmic effects of the class III agent almokalant: importance of infusion rate, QT dispersion, and early afterdepolarisations

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Use of arterially perfused rabbit ventricular wedge in predicting arrhythmogenic potentials of drugs

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Pharmacokinetics, safety, and tolerability of ascending single doses of moxifloxacin, a new 8-methoxy quinolone, administered to healthy subjects

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Notched T waves on Holter recordings enhance detection of patients with LQt2 (HERG) mutations

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2010.51

7 January 2021

Identifiers

DOI

10.1038/CLPT.2010.51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20485337%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference