(Q43081937)

English

Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design

scientific article published in April 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design (English)

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

0 references

equilibrium dynamics

1 reference

based on heuristic

inferred from title

protein crystallography

1 reference

based on heuristic

inferred from title

Joel L. Sussman

5

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

object named as

Martin Weik

6

0 references

author name string

Yechun Xu

1

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Jacques Ph Colletier

2

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Hualiang Jiang

3

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Israel Silman

4

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

publication date

1 April 2008

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Protein Science

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

17

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

4

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

601-605

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Exploring experimental sources of multiple protein conformations in structure-based drug design.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Evidence for a novel binding site conformer of aldose reductase in ligand-bound state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Application of a Theory of Enzyme Specificity to Protein Synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Acetylcholinesterase: 'classical' and 'non-classical' functions and pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Conformational changes associated with protein-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Antibody multispecificity mediated by conformational diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Three-dimensional structures ofDrosophila melanogasteracetylcholinesterase and of its complexes with two potent inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Specific chemical and structural damage to proteins produced by synchrotron radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Folding funnels, binding funnels, and protein function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

The Energy Landscapes and Motions of Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

25 May 2018

Conformational flexibility in the peripheral site of Torpedo californica acetylcholinesterase revealed by the complex structure with a bifunctional inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

15 August 2018

Interactions between the peripheral site and the acylation site in acetylcholinesterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

15 August 2018

GROMACS 3.0: a package for molecular simulation and trajectory analysis

1 reference

https://api.crossref.org/works/10.1110%2FPS.083453808

21 January 2018

Complexes of Alkylene-Linked Tacrine Dimers withTorpedo californicaAcetylcholinesterase: Binding of Bis(5)-tacrine Produces a Dramatic Rearrangement in the Active-Site Gorge

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2271175

1 December 2018

Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates

1 reference

https://pubmed.ncbi.nlm.nih.gov/18359854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1110/PS.083453808

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

ResearchGate publication ID

0 references

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