(Q43100244)

English

Adeno-associated viral (AAV) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces Abeta deposits in APP + PS1 transgenic mice

scientific article published on 29 July 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Adeno-associated viral (AAV) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces Abeta deposits in APP + PS1 transgenic mice (English)

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

1

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

author name string

Kevin Nash

2

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Daniel Lee

3

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Mary Mercer

4

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Paul E Gottschall

5

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Craig Meyers

6

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Nicholas Muzyczka

7

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Marcia N Gordon

8

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Dave Morgan

9

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

publication date

29 July 2008

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

Molecular Therapy

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

16

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

9

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

1580-1586

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

AAV8, 9, Rh10, Rh43 vector gene transfer in the rat brain: effects of serotype, promoter and purification method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706523

25 May 2018

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

1 reference

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Nerve growth factor gene therapy in Alzheimer disease

1 reference

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Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

1 reference

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25 May 2018

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

1 reference

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25 May 2018

Anti-Abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease

1 reference

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Recombinant adeno-associated viral vectors as therapeutic agents to treat neurological disorders.

1 reference

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25 May 2018

Abeta-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention

1 reference

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25 May 2018

Recombinant adeno-associated viral vectors in the nervous system

1 reference

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AAV hybrid serotypes: improved vectors for gene delivery

1 reference

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Targeting amyloid-degrading enzymes as therapeutic strategies in neurodegeneration

1 reference

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Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease

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Clinical trials in neurological disorders using AAV vectors: promises and challenges.

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Age-related changes in the properties of the endothelin receptor system at protein and mRNA levels in the rat vas deferens

1 reference

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Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain.

1 reference

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25 May 2018

Neprilysin gene transfer reduces human amyloid pathology in transgenic mice.

1 reference

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25 May 2018

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706523

25 May 2018

Production and purification of serotype 1, 2, and 5 recombinant adeno-associated viral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706523

25 May 2018

Heterodimerization of endothelin-converting enzyme-1 isoforms regulates the subcellular distribution of this metalloprotease

1 reference

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25 May 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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25 May 2018

A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP.

1 reference

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25 May 2018

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

1 reference

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25 May 2018

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706523

25 May 2018

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme

1 reference

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25 May 2018

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

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25 May 2018

Pharmacological characterization of a novel sulfonylureid-pyrazole derivative, SM-19712, a potent nonpeptidic inhibitor of endothelin converting enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2706523

25 May 2018

Adeno-associated virus-mediated gene transfer to the brain: duration and modulation of expression

1 reference

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Hydrolysis of peptide hormones by endothelin-converting enzyme-1. A comparison with neprilysin

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

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Rat endothelin-converting enzyme-1 forms a dimer through Cys412 with a similar catalytic mechanism and a distinct substrate binding mechanism compared with neutral endopeptidase-24.11

1 reference

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Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection

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Oral vaccination with a viral vector containing Abeta cDNA attenuates age-related Abeta accumulation and memory deficits without causing inflammation in a mouse Alzheimer model

1 reference

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Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice.

1 reference

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Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme.

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Protective effect of SM-19712, a novel and potent endothelin converting enzyme inhibitor, on ischemic acute renal failure in rats

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https://pubmed.ncbi.nlm.nih.gov/18665160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18665160

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based on heuristic

inferred from PubMed ID database lookup

Nerve growth factor and Alzheimer's disease

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https://pubmed.ncbi.nlm.nih.gov/18665160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MT.2008.148

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 November 2017

ResearchGate publication ID

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