(Q48535203)

English

Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice.

scientific article published in May 2006

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scholarly article

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Europe PubMed Central

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21 January 2020

Deglycosylated anti-amyloid-beta antibodies eliminate cognitive deficits and reduce parenchymal amyloid with minimal vascular consequences in aged amyloid precursor protein transgenic mice (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16707786%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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author name string

Donna M Wilcock

1

1 reference

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21 January 2020

Jennifer Alamed

2

1 reference

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21 January 2020

Paul E Gottschall

3

1 reference

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21 January 2020

Jan Grimm

4

1 reference

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21 January 2020

Arnon Rosenthal

5

1 reference

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21 January 2020

Jaume Pons

6

1 reference

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21 January 2020

Victoria Ronan

7

1 reference

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21 January 2020

Keisha Symmonds

8

1 reference

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21 January 2020

Marcia N Gordon

9

1 reference

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21 January 2020

Dave Morgan

10

1 reference

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21 January 2020

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publication date

1 May 2006

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21 January 2020

Journal of Neuroscience

1 reference

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21 January 2020

26

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21 January 2020

20

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21 January 2020

5340-5346

1 reference

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21 January 2020

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recognition of IgG by Fcgamma receptor. The role of Fc glycosylation and the binding of peptide inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation between cognitive deficits and Abeta deposits in transgenic APP+PS1 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebral hemorrhage after passive anti-Abeta immunotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta immunization effectively reduces amyloid deposition in FcRgamma-/- knock-out mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive immunotherapy against Abeta in aged APP-transgenic mice reverses cognitive deficits and depletes parenchymal amyloid deposits in spite of increased vascular amyloid and microhemorrhage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta vaccination effects on plaque pathology in the absence of encephalitis in Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exacerbation of cerebral amyloid angiopathy-associated microhemorrhage in amyloid precursor protein transgenic mice by immunotherapy is dependent on antibody recognition of deposited forms of amyloid beta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aglycosylation of human IgG1 and IgG3 monoclonal antibodies can eliminate recognition by human cells expressing Fc gamma RI and/or Fc gamma RII receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of pH treatments and deglycosylation of rabbit immunoglobulin G on the binding of C1q

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16707786

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0695-06.2006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16707786%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16707786%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16707786%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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