(Q43107676)

English

Improved insulin sensitivity, preserved beta cell function and improved whole-body glucose metabolism after low-dose growth hormone replacement therapy in adults with severe growth hormone deficiency: a pilot study.

scientific article published on 6 April 2010

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Improved insulin sensitivity, preserved beta cell function and improved whole-body glucose metabolism after low-dose growth hormone replacement therapy in adults with severe growth hormone deficiency: a pilot study (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Hormone Replacement Therapy

1 reference

based on heuristic

inferred from title

growth hormone deficiency

1 reference

based on heuristic

inferred from title

Ayman M. Arafat

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Martin O. Weickert

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Andreas Pfeiffer

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

author name string

M Möhlig

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

C Schöfl

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

J Spranger

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

publication date

6 April 2010

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

53

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1304-1313

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20372873%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1738-4

21 January 2018

Phlorrhizin diabetes in fasting or fed hypophysectomized dogs.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-010-1738-4

21 January 2018

Effects of 10 years of growth hormone (GH) replacement therapy in adult GH-deficient men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A low individualized GH dose in young patients with childhood onset GH deficiency normalized serum IGF-I without significant deterioration in glucose tolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pegvisomant increases intra-abdominal fat in patients with acromegaly: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative study of insulin secretion and clearance in normal and obese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of GH replacement in adult GH-deficient patients: changes in body composition without concomitant changes in the adipokines and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One year of GH replacement therapy with a fixed low-dose regimen improves body composition, bone mineral density and lipid profile of GH-deficient adults.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol 3-kinase contributes to insulin-like growth factor I-mediated inhibition of pancreatic beta-cell death.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone replacement therapy for adults: into the new millennium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of treatment with recombinant human GH and IGF-I on visceral adipose tissue and glucose homeostasis in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell capacity and insulin sensitivity in prepubertal children born small for gestational age: influence of body size during childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islets secretory capacity determines glucose homoeostasis in the face of insulin resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the rise in FFA by Acipimox partially prevents GH-induced insulin resistance in GH-deficient adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metasomatotrophic diabetes and its induction: basal insulin secretion and insulin release responses to glucose, glucagon, arginine and meals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of treatment with recombinant human growth hormone on insulin sensitivity and glucose metabolism in adults with growth hormone deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of insulin-like growth factor (IGF) binding protein-2 in the insulin-mediated decrease in IGF-I bioactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose dependency of the pharmacokinetics and acute lipolytic actions of growth hormone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic syndrome--a new worldwide definition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone replacement therapy induces insulin resistance by activating the glucose-fatty acid cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of low dose recombinant human growth hormone replacement on regional fat distribution, insulin sensitivity, and cardiovascular risk factors in hypopituitary adults.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Persisting effects on fasting glucose levels and insulin sensitivity after 6 months of discontinuation of a very low-dose GH therapy in adults with severe GH deficiency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of growth hormone on insulin action in man. Mechanisms of insulin resistance, impaired suppression of glucose production, and impaired stimulation of glucose utilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both insulin sensitivity and insulin clearance in children and young adults with Type I (insulin-dependent) diabetes vary with growth hormone concentrations and with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dose-response study of growth hormone (GH) replacement on whole body protein and lipid kinetics in GH-deficient adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term low-dose growth hormone administration in subjects with impaired glucose tolerance and the metabolic syndrome: effects on beta-cell function and post-load glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of insulin on glucose turnover rates in vivo: isotope dilution versus constant specific activity technique

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased insulin sensitivity is associated with reduced insulin and glucagon secretion and increased insulin clearance in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between premature mortality and hypopituitarism. West Midlands Prospective Hypopituitary Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of short-term administration of two low doses versus the standard GH replacement dose on insulin sensitivity and fasting glucose levels in young healthy adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of the deterioration of insulin sensitivity on beta-cell function in growth-hormone-deficient adults following 4-month growth hormone replacement therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose clamp technique: a method for quantifying insulin secretion and resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High incidence of cardiovascular disease and increased prevalence of cardiovascular risk factors in women with hypopituitarism not receiving growth hormone treatment: preliminary results

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of short and long-term growth hormone replacement therapy in hypopituitary adults on lipid metabolism and carbohydrate tolerance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Menstrual cyclicity has a profound effect on glucose homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of growth hormone on carbohydrate and lipid metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reference ranges for two automated chemiluminescent assays for serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 (IGFBP-3)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic aspects of growth hormone and insulin-like growth factor-I treatment on visceral fat and insulin sensitivity in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The metabolic effects of short-term administration of physiological versus high doses of GH therapy in GH deficient adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improvement in insulin sensitivity without concomitant changes in body composition and cardiovascular risk markers following fixed administration of a very low growth hormone (GH) dose in adults with severe GH deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone response during oral glucose tolerance test: the impact of assay method on the estimation of reference values in patients with acromegaly and in healthy controls, and the role of gender, age, and body mass index.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance, body fat distribution, and sex hormones in men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-Peptide as a Measure of the Secretion and Hepatic Extraction of Insulin: Pitfalls and Limitations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of 3 months of recombinant human growth hormone (GH) therapy on insulin and glucose-mediated glucose disposal and insulin secretion in GH-deficient adults: a minimal model analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20372873

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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