(Q43940568)

28 November 2017

title

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass (English)

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28 November 2017

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7

Kahn CR

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28 November 2017

Kulkarni RN

1

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28 November 2017

Holzenberger M

2

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28 November 2017

Shih DQ

3

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28 November 2017

Ozcan U

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28 November 2017

Stoffel M

5

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28 November 2017

Magnuson MA

6

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28 November 2017

language of work or name

English

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publication date

1 April 2002

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28 November 2017

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28 November 2017

volume

31

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28 November 2017

issue

1

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28 November 2017

page(s)

111-115

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https://scigraph.springernature.com/pub.10.1038/ng872

28 November 2017

exact match

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cites work

Islet cell growth and the growth factors involved

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7 January 2021

Pancreatic beta-cell growth and diabetes mellitus

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7 January 2021

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Evidence for the presence of type I insulin-like growth factor receptors on rat pancreatic A and B cells

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Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells

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7 January 2021

IGF-I and GH post-receptor signaling mechanisms for pancreatic beta-cell replication

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7 January 2021

Effects of growth hormone and insulin-like growth factor I on endocrine function of human fetal islet-like cell clusters during long-term tissue culture

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7 January 2021

Insulin and multiplication stimulating activity (an insulin-like growth factor) stimulate islet (beta-cell replication in neonatal rat pancreatic monolayer cultures

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7 January 2021

Ontogeny of fibroblast growth factors in the early development of the rat endocrine pancreas.

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7 January 2021

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

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7 January 2021

Induction of pancreatic differentiation by signals from blood vessels.

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7 January 2021

A targeted partial invalidation of the insulin-like growth factor I receptor gene in mice causes a postnatal growth deficit

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7 January 2021

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

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7 January 2021

Insulin-like growth factor-I at physiological concentrations is a potent inhibitor of insulin secretion

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7 January 2021

Regulation of a transcription factor network required for differentiation and metabolism

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7 January 2021

Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

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7 January 2021

Influence of genetic background on knockout mouse phenotypes

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7 January 2021

Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas

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7 January 2021

Enhanced insulin-like growth factor I gene expression in regenerating rat pancreas

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7 January 2021

Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

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7 January 2021

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways

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7 January 2021

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

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7 January 2021

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

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7 January 2021

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

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7 January 2021

Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication

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7 January 2021

Dimensions Publication ID

Identifiers

DOI

10.1038/NG872

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1003838979

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1 reference