(Q43116153)

English

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice

scientific article published on 16 September 2014

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

14 November 2017

Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice (English)

1 reference

Europe PubMed Central

14 November 2017

1 reference

based on heuristic

inferred from title

Ilie-Cosmin Stancu

object named as

Ilie-Cosmin Stancu

4

0 references

object named as

Luc Ver Donck

8

0 references

John Q. Trojanowski

15

object named as

John Q Trojanowski

1 reference

Europe PubMed Central

14 November 2017

author name string

Eve Peeraer

1

1 reference

Europe PubMed Central

14 November 2017

Astrid Bottelbergs

2

1 reference

Europe PubMed Central

14 November 2017

Kristof Van Kolen

3

1 reference

Europe PubMed Central

14 November 2017

Bruno Vasconcelos

5

1 reference

Europe PubMed Central

14 November 2017

Michel Mahieu

6

1 reference

Europe PubMed Central

14 November 2017

Hilde Duytschaever

7

1 reference

Europe PubMed Central

14 November 2017

An Torremans

9

1 reference

Europe PubMed Central

14 November 2017

Ellen Sluydts

10

1 reference

Europe PubMed Central

14 November 2017

Nathalie Van Acker

11

1 reference

Europe PubMed Central

14 November 2017

John A Kemp

12

1 reference

Europe PubMed Central

14 November 2017

Marc Mercken

13

1 reference

Europe PubMed Central

14 November 2017

Kurt R Brunden

14

1 reference

Europe PubMed Central

14 November 2017

Ilse Dewachter

16

1 reference

Europe PubMed Central

14 November 2017

Virginia M Y Lee

17

1 reference

Europe PubMed Central

14 November 2017

Diederik Moechars

18

1 reference

Europe PubMed Central

14 November 2017

publication date

16 September 2014

1 reference

Europe PubMed Central

14 November 2017

Neurobiology of Disease

1 reference

Europe PubMed Central

14 November 2017

73

1 reference

Europe PubMed Central

14 November 2017

83-95

1 reference

Europe PubMed Central

14 November 2017

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Prion-like spreading of pathological α-synuclein in brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Propagation of tau pathology in a model of early Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Trans-synaptic spread of tau pathology in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

The seeds of neurodegeneration: prion-like spreading in ALS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Characterization of tau fibrillization in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Induction of cerebral beta-amyloidosis: intracerebral versus systemic Abeta inoculation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Transmission and spreading of tauopathy in transgenic mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Propagation of tau misfolding from the outside to the inside of a cell.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Exogenous induction of cerebral beta-amyloidogenesis is governed by agent and host

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Peroxisomal multifunctional protein 2 is essential for lipid homeostasis in Sertoli cells and male fertility in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Mutations causing neurodegenerative tauopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Inflammation and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

A nucleated assembly mechanism of Alzheimer paired helical filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Neuropathological stageing of Alzheimer-related changes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

25 May 2018

Kainic acid-induced neuronal degeneration in hippocampal pyramidal neurons is driven by both intrinsic and extrinsic factors: analysis of FVB/N↔C57BL/6 chimeras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Constitutive secretion of tau protein by an unconventional mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Tau gene mutations and their effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Mouse strain differences in kainic acid sensitivity, seizure behavior, mortality, and hippocampal pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Exogenous induction of cerebral beta-amyloidosis in betaAPP-transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Detection of tau proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4303592

15 August 2018

Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25220759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25220759

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NBD.2014.08.032

1 reference

Europe PubMed Central

14 November 2017

1 reference

Europe PubMed Central

14 November 2017

1 reference

Europe PubMed Central

14 November 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43116153&oldid=1981208343"