(Q43120631)

14 November 2017

title

Effect of CYP2D6, CYP3A5, and MDR1 genetic polymorphisms on the pharmacokinetics of risperidone and its active moiety (English)

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14 November 2017

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Qian Xiang

1

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14 November 2017

Xia Zhao

2

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14 November 2017

Ying Zhou

3

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14 November 2017

Jing Li Duan

4

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14 November 2017

Yi Min Cui

5

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14 November 2017

publication date

23 March 2010

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The Journal of Clinical Pharmacology

14 November 2017

published in

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14 November 2017

volume

50

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14 November 2017

issue

6

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14 November 2017

page(s)

659-666

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Relationship between plasma risperidone and 9-hydroxyrisperidone concentrations and clinical response in patients with schizophrenia

14 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

ABCB1 pharmacogenetics: progress, pitfalls, and promise

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270009347867

Intestinal MDR transport proteins and P-450 enzymes as barriers to oral drug delivery

21 January 2018

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https://api.crossref.org/works/10.1177%2F0091270009347867

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Risperidone and paliperidone inhibit p-glycoprotein activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

The brain entry of risperidone and 9-hydroxyrisperidone is greatly limited by P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

ABCB1 polymorphisms influence steady-state plasma levels of 9-hydroxyrisperidone and risperidone active moiety.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Involvement of C3435T and G2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Atomoxetine pharmacokinetics in healthy Chinese subjects and effect of the CYP2D6*10 allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Effects of CYP2D6 genotypes on plasma concentrations of risperidone and enantiomers of 9-hydroxyrisperidone in Japanese patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Effect of rifampin, an inducer of CYP3A and P-glycoprotein, on the pharmacokinetics of risperidone

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: a clinically relevant pharmacokinetic drug interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

In vitro P-glycoprotein affinity for atypical and conventional antipsychotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Effect of verapamil on pharmacokinetics and pharmacodynamics of risperidone: in vivo evidence of involvement of P-glycoprotein in risperidone disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

Antipsychotic drugs inhibit the function of breast cancer resistance protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

In vitro P-glycoprotein assays to predict the in vivo interactions of P-glycoprotein with drugs in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0091270009347867

21 January 2018

Identifiers

DOI

10.1177/0091270009347867

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14 November 2017

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