(Q43122200)

14 November 2017

title

Hepatic CYP2B6 is altered by genetic, physiologic, and environmental factors but plays little role in nicotine metabolism (English)

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14 November 2017

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N Al Koudsi

1

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14 November 2017

R F Tyndale

series ordinal

2

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14 November 2017

language of work or name

English

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publication date

1 June 2010

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14 November 2017

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14 November 2017

volume

40

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14 November 2017

issue

6

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14 November 2017

page(s)

381-392

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Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors.

14 November 2017

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Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B6*6, is responsible for decreased expression and activity of CYP2B6 in liver

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CYP2B6 genotype does not alter nicotine metabolism, plasma levels, or abstinence with nicotine replacement therapy.

21 January 2018

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Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

21 January 2018

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21 January 2018

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21 January 2018

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The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

21 January 2018

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Growth hormone regulation of sex-dependent liver gene expression

21 January 2018

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Expression of constitutive androstane receptor, hepatic nuclear factor 4 alpha, and P450 oxidoreductase genes determines interindividual variability in basal expression and activity of a broad scope of xenobiotic metabolism genes in the human liver

21 January 2018

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21 January 2018

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21 January 2018

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Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

21 January 2018

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10.3109/00498251003713958

21 January 2018

Identifiers

DOI

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14 November 2017

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